B1 Vertaisarvioimaton kirjoitus tieteellisessä lehdessä
Small airway function in Finnish COVID-19 survivors
Tekijät: Lindahl Anna, Reijula Jere, Malmberg Leo Pekka, Aro Miia, Vasankari Tuula, Mäkelä Mika Juhani
Kustantaja: BMC
Julkaisuvuosi: 2021
Journal: Respiratory Research
Tietokannassa oleva lehden nimi: RESPIRATORY RESEARCH
Lehden akronyymi: RESP RES
Artikkelin numero: ARTN 237
Vuosikerta: 22
Numero: 1
Sivujen määrä: 5
eISSN: 1465-993X
DOI: https://doi.org/10.1186/s12931-021-01830-9
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/67273571
Tiivistelmä
Follow-up studies of COVID-19 patients have found lung function impairment up to six months after initial infection, but small airway function has not previously been studied. Patients (n = 20) hospitalised for a severe SARS-CoV-2 infection underwent spirometry, impulse oscillometry, and multiple measurements of alveolar nitric oxide three to six months after acute infection. None of the patients had small airway obstruction, nor increased nitric oxide concentration in the alveolar level. None of the patients had a reduced FEV1/FVC or significant bronchodilator responses in IOS or spirometry. In conclusion, we found no evidence of inflammation or dysfunction in the small airways.
Follow-up studies of COVID-19 patients have found lung function impairment up to six months after initial infection, but small airway function has not previously been studied. Patients (n = 20) hospitalised for a severe SARS-CoV-2 infection underwent spirometry, impulse oscillometry, and multiple measurements of alveolar nitric oxide three to six months after acute infection. None of the patients had small airway obstruction, nor increased nitric oxide concentration in the alveolar level. None of the patients had a reduced FEV1/FVC or significant bronchodilator responses in IOS or spirometry. In conclusion, we found no evidence of inflammation or dysfunction in the small airways.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
Turun yliopiston Tutkimustietojärjestelmän portaali