A1 Refereed original research article in a scientific journal
Tracheobronchial stents in patients with malignant airway disease: Finnish tertiary care experience
Authors: Routila Johannes, Herhi Eino, Korpi Jarkko, Pulkkinen Jaakko, Koivunen Petri, Rekola Jami
Publisher: Oxford university press
Publication year: 2021
Journal: Interactive Cardiovascular and Thoracic Surgery
Journal acronym: Interact Cardiovasc Thorac Surg
Article number: ivab147
DOI: https://doi.org/10.1093/icvts/ivab147
Web address : https://doi.org/10.1093/icvts/ivab147
Objectives: Tracheobronchial stenting has an established role in the palliation of malignant central airway obstruction (CAO). The purpose of this study is to describe the experience with self-expanding metal airway stents in 2 tertiary referral centres, covering a third of the population of Finland.
Patients and methods: Patients referred to and treated with airway stenting for malignant CAO using self-expanding metal-stents were identified from electronic patient records, and data were collected using a structured Endoscopic Lower Airway Management instrument. Statistical analysis to reveal factors affecting patient benefit and survival was carried out.
Results: A total of 101 patients (mean age 65.8) and 116 procedures were identified. Procedure-related mortality was rare (3/101 patients) and complications infrequent. The median survival was 2.3 months [95% confidence interval (CI): 1.4-3.1). Stent benefit was not significantly affected by clinical characteristics. Survival was impacted by the use of adjunct procedures [hazard ratio (HR) 0.36, 95% CI: 0.23-0.58, P < 0.001), procedural urgency (HR 0.40; 95% CI: 0.23-0.71, P = 0.002) and post-treatment chemoradiotherapy (HR 0.29, 95% CI: 0.15-0.56, P < 0.001).
Conclusions: The beneficial impact observed supports the further use of tracheobronchial stenting in malignant CAO. The use of self-expanding metal stents is encouraged.