A1 Refereed original research article in a scientific journal

Tracheobronchial stents in patients with malignant airway disease: Finnish tertiary care experience




AuthorsRoutila Johannes, Herhi Eino, Korpi Jarkko, Pulkkinen Jaakko, Koivunen Petri, Rekola Jami

PublisherOxford university press

Publication year2021

JournalInteractive Cardiovascular and Thoracic Surgery

Journal acronymInteract Cardiovasc Thorac Surg

Article numberivab147

DOIhttps://doi.org/10.1093/icvts/ivab147

Web address https://doi.org/10.1093/icvts/ivab147


Abstract

Objectives: Tracheobronchial stenting has an established role in the palliation of malignant central airway obstruction (CAO). The purpose of this study is to describe the experience with self-expanding metal airway stents in 2 tertiary referral centres, covering a third of the population of Finland.

Patients and methods: Patients referred to and treated with airway stenting for malignant CAO using self-expanding metal-stents were identified from electronic patient records, and data were collected using a structured Endoscopic Lower Airway Management instrument. Statistical analysis to reveal factors affecting patient benefit and survival was carried out.

Results: A total of 101 patients (mean age 65.8) and 116 procedures were identified. Procedure-related mortality was rare (3/101 patients) and complications infrequent. The median survival was 2.3 months [95% confidence interval (CI): 1.4-3.1). Stent benefit was not significantly affected by clinical characteristics. Survival was impacted by the use of adjunct procedures [hazard ratio (HR) 0.36, 95% CI: 0.23-0.58, P < 0.001), procedural urgency (HR 0.40; 95% CI: 0.23-0.71, P = 0.002) and post-treatment chemoradiotherapy (HR 0.29, 95% CI: 0.15-0.56, P < 0.001).

Conclusions: The beneficial impact observed supports the further use of tracheobronchial stenting in malignant CAO. The use of self-expanding metal stents is encouraged.



Last updated on 2024-26-11 at 18:37