A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Molecular epidemiology and evolutionary trajectory of emerging echovirus 30, Europe
Tekijät: Benschop Kimberley S.M., Broberg Eeva, Hodcroft Emma, Schmitz Dennis, Albert Jan, Baicus Anda, Bailly Jean,Luc, Baldvinsdottir Gudrun, Berginc Natasa, Blomqvist Soile, Böttcher Sindy, Brytting Mia, Bujaki Erika, Cabrerizo Maria, Celma Cristina, Cinek Ondrej, Claas Eric C.J., Cremer Jeroen, Dean Jonathan, Dembinski Jennifer, Demchyshyna Iryna, Diedrich Sabine, Dudman Susanne, Dunning Jake, Dyrdak Robert, Emmanouil Mary, Farkas Agnes, De Gascun Cillian, Fournier Guillme, Georgieva Irina, Gonzalez Sanz Ruben, van Hooydonk Elving Jolanda, Jääskeläinen Anne, Jancskaite Ruta, Keeren Kathrin, Fischer Thea, Krokstad Sidsel, Nikolaeva-Glomb Lubomira, Novakova Ludmila, Midgley Sofie, Mirand Drey, Molenkamp Richard, Morley Ursula, Mossong Joël, Muralyte Svajune, Murk Jean,Luc, Nguyen Trung, Nordbø Svein, Österback Riikka, Pas Suzan, Pellegrinelli Lra, Pogka Vassiliki, Prochazka Birgit, Rainetova Petra, Van Ranst Marc, Roorda Lieuwe, Schuffenecker Isabelle, Schuurman Rob, Stoyanova Asya, Templeton Kate, Verweij Jaco, Voulgari,Kokota Androniki, Vuorinen Tytti, Wollants Elke, Wolthers Katja, Zakikhany Katherina, Neher Richard, Harvala Heli, Simmonds Peter
Kustantaja: Centers for Disease Control and Prevention (CDC)
Julkaisuvuosi: 2021
Journal: Emerging Infectious Diseases
Tietokannassa oleva lehden nimi: Emerging Infectious Diseases
Vuosikerta: 27
Numero: 6
Aloitussivu: 1616
Lopetussivu: 1626
eISSN: 1080-6059
DOI: https://doi.org/10.3201/eid2706.203096
Verkko-osoite: https://doi.org/10.3201/eid2706.203096
In 2018, an upsurge in echovirus 30 (E30) infections was reported in
Europe. We conducted a large-scale epidemiologic and evolutionary study
of 1,329 E30 strains collected in 22 countries in Europe during
2016–2018. Most E30 cases affected persons 0–4 years of age (29%) and
25–34 years of age (27%). Sequences were divided into 6 genetic clades
(G1–G6). Most (53%) sequences belonged to G1, followed by G6 (23%), G2
(17%), G4 (4%), G3 (0.3%), and G5 (0.2%). Each clade encompassed unique
individual recombinant forms; G1 and G4 displayed >2
unique recombinant forms. Rapid turnover of new clades and recombinant
forms occurred over time. Clades G1 and G6 dominated in 2018, suggesting
the E30 upsurge was caused by emergence of 2 distinct clades
circulating in Europe. Investigation into the mechanisms behind the
rapid turnover of E30 is crucial for clarifying the epidemiology and
evolution of these enterovirus infections.
