A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Impact of temperature on obstructive sleep apnoea in three different climate zones of Europe: Data from the European Sleep Apnoea Database (ESADA)
Tekijät: Staats Richard, Bailly Sébastien, Bonsignore Maria Rosaria, Ryan Silke, Riha Renata L, Schiza Sophia, Verbraecken Johan, Basoglu Ozen K, Saaresranta Tarja, Pataka Athanasia, Ludka Ondrej, Lombardi Carolina, Hedner Jan Anders, Grote Ludger; European Sleep Apnoea Database (ESADA) collaborators
Kustantaja: WILEY
Julkaisuvuosi: 2021
Journal: Journal of Sleep Research
Tietokannassa oleva lehden nimi: JOURNAL OF SLEEP RESEARCH
Lehden akronyymi: J SLEEP RES
Artikkelin numero: ARTN e13315
Vuosikerta: 30
Numero: 5
Sivujen määrä: 11
ISSN: 0962-1105
eISSN: 1365-2869
DOI: https://doi.org/10.1111/jsr.13315
Verkko-osoite: https://doi.org/10.1111/jsr.13315
Recent studies indicate that ambient temperature may modulate obstructive sleep apnoea (OSA) severity. However, study results are contradictory warranting more investigation in this field. We analysed 19,293 patients of the European Sleep Apnoea Database (ESADA) cohort with restriction to the three predominant climate zones according to the Koppen-Geiger climate classification: Cfb (warm temperature, fully humid, warm summer), Csa (warm temperature, summer dry, hot summer), and Dfb (snow, fully humid, warm summer). Average outside temperature values were obtained and several hierarchical regression analyses were performed to investigate the impact of temperature on the apnea-hypopnea index (AHI), oxygen desaturation index (ODI), time of oxygen saturation <90% (T90) and minimum oxygen saturation (MinSpO(2)) after controlling for confounders including age, body mass index, gender, and air conditioning (A/C) use. AHI and ODI increased with higher temperatures with a standardised coefficient beta (beta) of 0.28 for AHI and 0.25 for ODI, while MinSpO(2) decreased with a beta of -0.13 (all results p < .001). When adjusting for climate zones, the temperature effect was only significant in Cfb (AHI: beta = 0.11) and Dfb (AHI: beta = 0.08) (Model 1: p < .001). The presence of A/C (3.9% and 69.3% in Cfab and Csa, respectively) demonstrated only a minor increase in the prediction of the variation (Cfb: AHI, R-2 +0.003; and Csa: AHI, R-2 +0.007; both p < .001). Our present study indicates a limited but consistent influence of environmental temperature on OSA severity and this effect is modulated by climate zones.
