A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Burden of allergic rhinitis and impact of MP-AzeFlu from the patient perspective: pan European patient survey
Tekijät: Canonica G Walter, Klimek Ludger, Acaster Sarah, Dollner Ralph, Kaulsay Ranbir, Lo Siu Hing, Price David B, Scadding Glenis K, Valovirta Erkka, Zieglmayer Petra
Kustantaja: TAYLOR & FRANCIS LTD
Julkaisuvuosi: 2021
Journal: Current Medical Research and Opinion
Tietokannassa oleva lehden nimi: CURRENT MEDICAL RESEARCH AND OPINION
Lehden akronyymi: CURR MED RES OPIN
Vuosikerta: 37
Numero: 7
Aloitussivu: 1259
Lopetussivu: 1272
Sivujen määrä: 14
ISSN: 0300-7995
eISSN: 1473-4877
DOI: https://doi.org/10.1080/03007995.2021.1911973
Verkko-osoite: https://www.tandfonline.com/doi/full/10.1080/03007995.2021.1911973
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/56055729
Objective
The aims of this survey were to (1) assess the burden of allergic rhinitis (AR) from the patient perspective, (2) investigate MP-AzeFlu use in real life and its impact on patients' lives and (3) explore factors associated with treatment satisfaction.
Methods
A cross-sectional, quantitative, online, questionnaire-based survey was conducted in seven European countries (March-June 2019). Questions explored AR burden and treatment satisfaction. Satisfaction was assessed using the Treatment Satisfaction Questionnaire for Medication 9-item (TSQM-9; max score = 100). Participants (aged >= 18 years) had a doctor/healthcare provider confirmed AR diagnosis and used MP-AzeFlu within the last year.
Results
Pre-MP-AzeFlu treatment, participants (n = 1004) reported an average of 3.3 (SD:3.5) doctor visits/year, 8.1 (SD:11.0) days/year absenteeism and 15.8 (SD:18.9) days/year presenteeism due to AR. Only 48% of participants used MP-AzeFlu twice/day as recommended. Post-MP-AzeFlu 57% of participants reported better QoL, 47% reported fewer doctor visits and 52% discontinued polypharmacy. Absenteeism and presenteeism were reduced by 2.5 (SD 10.0) and 7.3 (SD:16.0) days/year, respectively. 70% of participants were more/much more satisfied with MP-AzeFlu versus previous AR treatment(s), and >= 70% were satisfied/extremely satisfied with its ability to prevent/treat AR, relieve symptoms and with its onset of action. Mean global, effectiveness and convenience TSQM-9 scores were 70.0 (SD:19.8), 68.3 (SD:21.6) and 72.7 (SD:20.4), respectively. Treatment satisfaction and effectiveness were significantly improved when MP-AzeFlu was taken as recommended.
Conclusions
The impact of AR on patients' lives remains high. Real-life use of MP-AzeFlu reduces that impact and is associated with a high level of effectiveness, convenience and global satisfaction.
Ladattava julkaisu This is an electronic reprint of the original article. |