A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
[Pepmhigus of the mucous membrane of the mouth].
Tekijät: Haimala A, Väkevä L, Häyry V, Hagström J
Julkaisuvuosi: 2014
Journal: Duodecim
Tietokannassa oleva lehden nimi: Duodecim; laaketieteellinen aikakauskirja
Lehden akronyymi: Duodecim
Vuosikerta: 130
Numero: 7
Aloitussivu: 696
Lopetussivu: 9
ISSN: 0012-7183
Tiivistelmä
Pemphigus is a rare autoimmune disease of the skin and mucous membranes. It is characterized by autoantibodies directed against the desmosomal adhesion proteins of epithelial cells (desmoglein type I and III) resulting in acantholysis of the epithelium. Painful blisters or erosions are typical clinical findings. Pemphigus is a severe disease that may be fatal. Early diagnosis of pemphigus is important in order to be able to start the treatment as soon as possible and to halt the progression of the disease and avoid serious secondary infections.
Pemphigus is a rare autoimmune disease of the skin and mucous membranes. It is characterized by autoantibodies directed against the desmosomal adhesion proteins of epithelial cells (desmoglein type I and III) resulting in acantholysis of the epithelium. Painful blisters or erosions are typical clinical findings. Pemphigus is a severe disease that may be fatal. Early diagnosis of pemphigus is important in order to be able to start the treatment as soon as possible and to halt the progression of the disease and avoid serious secondary infections.
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