A2 Refereed review article in a scientific journal
[Pepmhigus of the mucous membrane of the mouth].
Authors: Haimala A, Väkevä L, Häyry V, Hagström J
Publication year: 2014
Journal: Duodecim
Journal name in source: Duodecim; laaketieteellinen aikakauskirja
Journal acronym: Duodecim
Volume: 130
Issue: 7
First page : 696
Last page: 9
ISSN: 0012-7183
Abstract
Pemphigus is a rare autoimmune disease of the skin and mucous membranes. It is characterized by autoantibodies directed against the desmosomal adhesion proteins of epithelial cells (desmoglein type I and III) resulting in acantholysis of the epithelium. Painful blisters or erosions are typical clinical findings. Pemphigus is a severe disease that may be fatal. Early diagnosis of pemphigus is important in order to be able to start the treatment as soon as possible and to halt the progression of the disease and avoid serious secondary infections.
Pemphigus is a rare autoimmune disease of the skin and mucous membranes. It is characterized by autoantibodies directed against the desmosomal adhesion proteins of epithelial cells (desmoglein type I and III) resulting in acantholysis of the epithelium. Painful blisters or erosions are typical clinical findings. Pemphigus is a severe disease that may be fatal. Early diagnosis of pemphigus is important in order to be able to start the treatment as soon as possible and to halt the progression of the disease and avoid serious secondary infections.