A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Organomercury Nucleic Acids: Past, Present and Future
Tekijät: Ukale Dattatraya, Lönnberg Tuomas
Kustantaja: WILEY-V C H VERLAG GMBH
Julkaisuvuosi: 2021
Journal: ChemBioChem
Tietokannassa oleva lehden nimi: CHEMBIOCHEM
Lehden akronyymi: CHEMBIOCHEM
Sivujen määrä: 8
ISSN: 1439-4227
eISSN: 1439-7633
DOI: https://doi.org/10.1002/cbic.202000821
Verkko-osoite: https://doi.org/10.1002/cbic.202000821
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/53412356
Tiivistelmä
Synthetic efforts towards nucleosides, nucleotides, oligonucleotides and nucleic acids covalently mercurated at one or more of their base moieties are summarized, followed by a discussion of the proposed, realized and abandoned applications of this unique class of compounds. Special emphasis is given to fields in which active research is ongoing, notably the use of Hg-II-mediated base pairing to improve the hybridization properties of oligonucleotide probes. Finally, this minireview attempts to anticipate potential future applications of organomercury nucleic acids.
Synthetic efforts towards nucleosides, nucleotides, oligonucleotides and nucleic acids covalently mercurated at one or more of their base moieties are summarized, followed by a discussion of the proposed, realized and abandoned applications of this unique class of compounds. Special emphasis is given to fields in which active research is ongoing, notably the use of Hg-II-mediated base pairing to improve the hybridization properties of oligonucleotide probes. Finally, this minireview attempts to anticipate potential future applications of organomercury nucleic acids.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
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