A1 Refereed original research article in a scientific journal
Adaptation of bacteria to glyphosate: a microevolutionary perspective of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase
Authors: Rainio Miia J, Ruuskanen Suvi, Helander Marjo, Saikkonen Kari, Saloniemi Irma, Puigbò Pere
Publisher: WILEY
Publication year: 2021
Journal: Environmental Microbiology Reports
Journal name in source: ENVIRONMENTAL MICROBIOLOGY REPORTS
Journal acronym: ENV MICROBIOL REP
Number of pages: 8
ISSN: 1758-2229
eISSN: 1758-2229
DOI: https://doi.org/10.1111/1758-2229.12931
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/53327474
Glyphosate is the leading herbicide worldwide, but it also affects prokaryotes because it targets the central enzyme (5-enolpyruvylshikimate-3-phosphate, EPSP) of the shikimate pathway in the synthesis of the three essential aromatic amino acids in bacteria, fungi and plants. Our results reveal that bacteria may easily become resistant to glyphosate through changes in the 5-enolpyruvylshikimate-3-phosphate synthase active site. This indicates the importance of examining how glyphosate affects microbe-mediated ecosystem functions and human microbiomes.
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