A1 Refereed original research article in a scientific journal
Climacteric symptoms among full-time working HRT never-users in different work environments: a cross-sectional study; 
Authors: Lipasti, Maija; Jalava-Broman, Jaana; Sillanmäki, Lauri; Mäkinen, Juha; Rautava, Päivi
Publisher: Informa UK Limited
Publication year: 2026
Journal: Journal of Obstetrics and Gynaecology
Article number: 2678186
Volume: 46
Issue: 1
ISSN: 0144-3615
eISSN: 1364-6893
DOI: https://doi.org/10.1080/01443615.2026.2678186
Publication's open availability at the time of reporting: Open Access
Publication channel's open availability : Open Access publication channel
Web address : https://doi.org/10.1080/01443615.2026.2678186
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/523621253
Self-archived copy's licence: CC BY
Self-archived copy's version: Publisher`s PDF
Background
Climacteric symptoms affect a large and growing proportion of women worldwide. Furthermore, women are increasingly participating in the workforce. Many women do not use treatment for their symptoms; however, little is known about how untreated women experience climacteric symptoms. This study examined the occurrence and severity of climacteric symptoms among full-time working women before treatment and compared their experiences across two different work environments.
MethodsA cross-sectional study was conducted in a group of Finnish women aged 52–66 years who had never used any treatment for their climacteric symptoms and were employed full-time. The data were obtained from two population-based postal surveys. Statistical techniques were used to analyse the data.
ResultsThe most common symptoms among all participants (n = 338) were hot flushes (80%), sweats (72%), and sleeping problems (72%). The most severe symptoms were hot flushes, sweats, and loss of sexual desire; 12% of participants experienced each of these as severe. Regarding symptom categories, vasomotor symptoms and loss of sexual desire were the most common and the most severe. Participants in either low-strain or high-strain jobs (n = 164) most often experienced five (15%) or 10 (13%) different symptoms out of 12 presented in the study questionnaire. Participants in high-strain jobs (n = 79) experienced a higher number of symptoms (p = 0.019) and more often urinary incontinence (p = 0.008) and depressive symptoms (p = 0.043) than those in low-strain jobs (n = 85). Furthermore, they experienced more severe sweats (p = 0.038).
ConclusionsHot flushes, sweats, sleeping problems, and loss of sexual desire were both common and severe among full-time working untreated women. In addition, symptoms were more troublesome among women in high-strain than low-strain jobs. Therefore, healthcare professionals should pay special attention to the above symptoms and to women in high-strain jobs.
Keywords:
Climacteric symptoms, Cross‐sectional studies, Hormone replacement therapy, Menopause, Survey, Working conditions
Downloadable publication This is an electronic reprint of the original article. |
Funding information in the publication:
M.L. and P.R. were supported by State Research Funding (VTR) for university-level health research.