A2 Refereed review article in a scientific journal
Coexistent Endometrial and Ovarian Carcinoma: Terminology, Clinicopathological Features, and Clinical Significance
Authors: Huvila, Jutta; Gilks, C. Blake; McAlpine, Jessica N.; Jamieson, Amy
Publisher: Lippincott
Publication year: 2026
Journal: International Journal of Gynecologic Pathology
ISSN: 0277-1691
eISSN: 1538-7151
DOI: https://doi.org/10.1097/PGP.0000000000001177
Publication's open availability at the time of reporting: No Open Access
Publication channel's open availability : Partially Open Access publication channel
Web address : https://doi.org/10.1097/pgp.0000000000001177
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/523102772
Self-archived copy's version: Final draft
Carcinoma simultaneously involving the endometrium and ovary is encountered frequently enough in clinical practice that guidelines are needed for consistent surgical pathology reporting and patient management. This review will cover the history and terminology of this phenomenon, summarize current practices, and provide a practical reporting framework for daily use. By focusing on conventional surgical pathology parameters, including molecular subtype, while avoiding clonality considerations, it is possible to consistently provide the necessary information to guide treatment. There remain some outstanding issues that require further research, which will be identified and discussed.
Keywords:
co-existent, co-existent endometrial and ovarian carcinoma, endometrial carcinoma, molecular subtypes, Ovarian carcinoma, synchronous, synchronous endometrial and ovarian carcinoma
Funding information in the publication:
This work was supported by funding from the Terry Fox Research Foundation (J.N.M.).
