A1 Refereed original research article in a scientific journal

Participation in a 20‐Year Randomized Dietary Trial and University Enrollment




AuthorsViinikainen, Jutta; Heineck, Guido; Böckerman, Petri; Pahkala, Katja; Jula, Antti; Kari, Jaana T.; Lagström, Hanna; Niinikoski, Harri; Pehkonen, Jaakko; Rovio, Suvi P.; Rönnemaa, Tapani; Salo, Pia; Viikari, Jorma; Raitakari, Olli

Publication year2026

Journal: Health science reports

Article numbere72359

Volume9

Issue4

eISSN2398-8835

DOIhttps://doi.org/10.1002/hsr2.72359

Publication's open availability at the time of reportingOpen Access

Publication channel's open availability Open Access publication channel

Web address https://doi.org/10.1002/hsr2.72359

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/523101648

Self-archived copy's licenceCC BY

Self-archived copy's versionPublisher`s PDF


Abstract
Background and Aims

A nutritionally balanced, age-appropriate diet is crucial for child development. The randomized Special Turku Coronary Risk Factor Intervention Project (STRIP) was a 20-year dietary intervention starting at 7 months of age. It aimed at improving fat quality and promoting healthy foods to prevent cardiovascular diseases. We examined whether the intervention was associated with university enrollment and difficulties in school-related tasks in a post hoc setting.

Methods

Participants (n = 1062) were recruited at the age of 5 months between December 1, 1989, and May 30, 1992, from child health clinics in Turku, Finland, and were randomly assigned to either the intervention (n = 541) or control group (n = 521) at the age of 7 months. Children in the intervention group received personalized dietary counseling through age 20, without a fixed diet. We used linear probability models estimated by ordinary least squares (OLS) to investigate whether being in the intervention group was associated with university enrollment by age 26, and OLS regressions to examine its association with difficulties in school-related tasks at age 10. The study is reported in accordance with the CONSORT guidelines.

Results

In total, 639 participants provided university enrollment data. Among males from low-education families, being in the intervention group was associated with a 32 percentage point higher likelihood of enrollment (b = 0.324, p = 0.004, 95% confidence interval (CI): 0.103, 0.546). Among all males the association was 11 percentage points (b = 0.107, p = 0.07, 95% CI: −0.007, 0.220), and among females −3 percentage points (b = −0.033, p = 0.53, 95% CI: −0.137, 0.071). The results also suggested that diet, rather than cardiovascular health, may serve as a mediator.

Conclusions

Long-term dietary counseling is associated with increased educational attainment among males from low-education families. The study is registered at ClinicalTrials.gov (#NCT00223600).


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Funding information in the publication
The STRIP study was supported by Academy of Finland (grants 206374, 294834, 251360, 275595, 307996, 322112); Finnish Cultural Foundation; Finnish Foundation for Cardiovascular Research; Finnish Ministry of Education and Culture; Finnish Medical Foundation; Juho Vainio Foundation; Sigrid Juselius Foundation; Special Governmental grants for Health Sciences Research (Turku University Hospital); Turku University Foundation; and Yrjö Jahnsson Foundation. The funders had no role in the study design, data collection, analysis, or interpretation, writing of the report, or the decision to submit the report for publication. Open access publishing facilitated by Jyvaskylan yliopisto, as part of the Wiley - FinELib agreement.


Last updated on 30/04/2026 10:17:46 AM