A1 Refereed original research article in a scientific journal
International expert consensus on definitions and management of weight recurrence and suboptimal response after metabolic and bariatric surgery: a Delphi study; 
Authors: Wills, Mélissa V.; Lee, Sol; Mocanu, Valentin; Lee, Yung; Kachornvitaya, Pattharasai; Zhu, Xinlei; Alfaris, Nasreen; Andromalos, Laura; Apovian, Caroline; Behrens, Estuardo; Birk, Dieter; Busetto, Luca; Courcoulas, Anita; Cummings, David; Faria Leite, Silvia; Ghanem, Omar; Han, Sang-Moon; Karmali, Shahzeer; Kaplan, Lee; Kow, Lilian; le Roux, Carel W.; Mahawar, Kamal; Gawdat, Khaled; Munoz, Rodrigo; Musella, Mario; Nimeri, Abdelrahman; O'Kane, Mary; Palermo, Mariano; Ponce de Leon Ballesteros, Guillermo; Salminen, Paulina; Sullivan, Shelby; Udomsawaengsup, Suthep; Tewksbury, Colleen; Vidal, Josep; Wilding, John; Dang, Jerry; Strong, Andrew; Navarrete, Salvador; Zundel, Natan; Kermansaravi, Mohammad; Butsch, Scott; Kroh, Matthew; Corcelles, Ricard
Publisher: Elsevier BV
Publication year: 2026
Journal: Surgery for Obesity and Related Diseases
Volume: 22
Issue: 7
First page : 753
Last page: 761
ISSN: 1550-7289
eISSN: 1878-7533
DOI: https://doi.org/10.1016/j.soard.2026.03.006
Publication's open availability at the time of reporting: Open Access
Publication channel's open availability : Partially Open Access publication channel
Web address : https://doi.org/10.1016/j.soard.2026.03.006
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/522982011
Self-archived copy's licence: CC BY NC ND
Self-archived copy's version: Publisher`s PDF
Background: Weight recurrence and suboptimal response after metabolic and bariatric surgery (MBS) lack standardized definitions and management approaches, creating barriers to evidence-based treatment decisions and coordinated care across multiple specialties.
Objectives: To establish international expert consensus on terminology, diagnostic approaches, and management strategies for suboptimal response and weight recurrence after MBS.
Setting: International Delphi study across multiple countries and health care systems.
Methods: A two-round modified Delphi study was conducted with 66 international experts across five specialties (MBS, obesity medicine, gastroenterology, endocrinology, dietetics and nutrition, and psychology). A 164-item questionnaire was developed, spanning seven dimensions: conservative management, diagnostic methods, endoscopic interventions, quantitative thresholds, risk factors, surgical interventions, and terminology. Consensus was defined a priori as ≥70% agreement. Inter-rater reliability was assessed using Gwet's AC1 coefficient.
Results: Response rates were 54.5% (Round 1) and 57.6% (Round 2). Consensus achievement improved significantly between rounds (26.2% to 40.9% of items). Experts reached unanimous agreement on core management principles including individualized patient care (100%) and the appropriateness of specialists prescribing antiobesity medications (100%). Strong consensus emerged on standardized terminology with "suboptimal" as the preferred term (89.5%) and %TWL as the optimal measurement approach (94.6). For quantitative thresholds, consensus was achieved on surgical nonresponse defined as <10% TWL at 12 months (73.0%), recurrent weight gain as >25% of lost weight from nadir (70.3%), and a 10% change in %EWL from nadir as normal physiologic response (83.8%). Conservative management items achieved the highest consensus rates (80.9%) while quantitative threshold items require additional research (28.1%). Inter-rater reliability improved across all domains, with conservative management achieving substantial agreement (AC1 = .70).
Conclusion: Expert consensus was achieved on fundamental principles of postbariatric care, including preferred terminology, measurement metrics, and provider roles. These recommendations address important gaps in clinical practice standardization.
Keywords:
Delphi consensus, Metabolic surgery, Obesity management medications, Revisional surgery, Suboptimal response, Weight recurrence
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Funding information in the publication:
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.