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Steam-assisted respiratory muscle training may improve sleep quality in mild-to-moderate obstructive sleep apnea: a pilot polysomnography study




TekijätAl-Rammahi, Usame; Soukka, Tero; Rimpilä, Ville; Malinen, J.; Happonen, Risto-Pekka; Sovijärvi, A.; Anttalainen, Ulla

Julkaisuvuosi2026

Lehti: Journal of Clinical Sleep Medicine

Artikkelin numero32

Vuosikerta22

Numero1

ISSN1550-9389

eISSN1550-9397

DOIhttps://doi.org/10.1007/s44470-025-00036-w

Julkaisun avoimuus kirjaamishetkelläAvoimesti saatavilla

Julkaisukanavan avoimuus Osittain avoin julkaisukanava

Verkko-osoitehttps://doi.org/10.1007/s44470-025-00036-w

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/515656742

Rinnakkaistallenteen lisenssiCC BY

Rinnakkaistallennetun julkaisun versioKustantajan versio


Tiivistelmä
Study objectives

Obstructive sleep apnea (OSA) impairs sleep and respiration, and sub-optimal adherence to its gold-standard CPAP therapy compels development of alternative approaches. This study investigates the effects of steam-assisted respiratory muscle training (RMT) on polysomnographic (PSG) outcomes in patients with OSA.

Methods

In a 12-week open-label prospective pilot study, 60 working participants with mild to moderate OSA underwent individualized inspiratory and expiratory resistance training with adjunctive steam inhalation. PSG was conducted pre- and post-intervention. Primary outcomes included changes in respiratory indices (AHI, ODI₃, CT₉₀) and sleep quality metrics (sleep efficiency, WASO). Statistical analyses included the Shapiro-Wilk normality test, Paired T, Welch, or Wilcoxon comparing visits, Wilson CIs reporting responders, Mann-Whitney and Fisher assessing associations, regression predicting change, with significance set at p < 0.05.

Results

Of 60 participants, 33 completed the study. Primary outcomes–respiratory indices and sleep continuity metrics–remained unchanged (all p > 0.05). Secondary analyses showed reduced REM latency, increased REM duration, and fewer periodic limb movements and arousal-related events (all p < 0.05). Regression analysis indicated that greater height and BMI were associated with fewer PLM, whereas larger waist circumference predicted more PLM.

Discussion

Steam-assisted RMT did not significantly alter respiratory or sleep continuity indices but was associated with modest changes in REM architecture and limb movements. These findings should be interpreted cautiously, as exploratory observations in a non-controlled pilot setting. Larger randomized, sham-controlled trials with objective adherence monitoring are warranted to confirm these preliminary results.


Ladattava julkaisu

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Julkaisussa olevat rahoitustiedot
Open Access funding provided by University of Turku (including Turku University Central Hospital). This study was supported by grants from the TYKS Foundation and the Research Foundation of the Pulmonary Diseases, Väinö and Laina Kivi Foundation and The Finnish Anti-Tuberculosis Association Foundation.


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