A1 Refereed original research article in a scientific journal
Is sleep apnea a risk factor for Covid-19? findings from a retrospective cohort study
Authors: Thijs Feuth, Tarja Saaresranta, Antti Karlsson, Mika Valtonen, Ville Peltola, Esa Rintala, Jarmo Oksi
Publication year: 2020
Journal: Sleep Medicine and Disorders: International Journal
Journal acronym: Sleep Med Dis Int J
Volume: 4
Issue: 3
First page : 61
Last page: 65
DOI: https://doi.org/10.15406/smdij.2020.04.00075
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/51269629
Background: In the early phase of the coronavirus disease-19 (Covid-19) pandemic, Southwest Finland remained relatively spared. By the 3rd of May 2020, a total of 28 patients have been admitted to the Turku University Hospital. We explore baseline characteristics in order to identify risk for severe disease and critical care admission.
Methods: For this retrospective cohort study, data were derived from hospital records. Basic descriptive statistics were used to characterise patients, including medians, percentiles and frequencies. Differences were tested with Mann Whitney U-test and Pearson’s chi-square test.
Results: Pre-existent obstructive sleep apnea (OSA) was present in 29% of patients admitted in the hospital for Covid-19. Overall, other findings on admission were comparable with those reported elsewhere. C-reactive protein and procalcitonin were higher in patients who were eventually transferred to critical care in comparison to in those who were not (median CRP 187 mg/L versus 52 mg/L, p<0.005 and median PCT 0.46 versus 0.12, p=0.047).
Conclusion: OSA was pre-existent in a disproportional large group of patients, which suggests that it is an important risk factor for severe Covid-19. Furthermore, we identified high CRP, PCT and possibly native oxygen saturation as useful clinical measures to identify patients at risk for critical care.
Downloadable publication This is an electronic reprint of the original article. |