Refereed journal article or data article (A1)

Is sleep apnea a risk factor for Covid-19? findings from a retrospective cohort study




List of Authors: Thijs Feuth, Tarja Saaresranta, Antti Karlsson, Mika Valtonen, Ville Peltola, Esa Rintala, Jarmo Oksi

Publication year: 2020

Journal: Sleep Medicine and Disorders: International Journal

Journal acronym: Sleep Med Dis Int J

Volume number: 4

Issue number: 3

DOI: http://dx.doi.org/10.15406/smdij.2020.04.00075

Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/51269629


Abstract

Background: In the early phase of the coronavirus disease-19 (Covid-19) pandemic, Southwest Finland remained relatively spared. By the 3rd of May 2020, a total of 28 patients have been admitted to the Turku University Hospital. We explore baseline characteristics in order to identify risk for severe disease and critical care admission.

Methods: For this retrospective cohort study, data were derived from hospital records. Basic descriptive statistics were used to characterise patients, including medians, percentiles and frequencies. Differences were tested with Mann Whitney U-test and Pearson’s chi-square test.

Results: Pre-existent obstructive sleep apnea (OSA) was present in 29% of patients admitted in the hospital for Covid-19. Overall, other findings on admission were comparable with those reported elsewhere. C-reactive protein and procalcitonin were higher in patients who were eventually transferred to critical care in comparison to in those who were not (median CRP 187 mg/L versus 52 mg/L, p<0.005 and median PCT 0.46 versus 0.12, p=0.047).

Conclusion: OSA was pre-existent in a disproportional large group of patients, which suggests that it is an important risk factor for severe Covid-19. Furthermore, we identified high CRP, PCT and possibly native oxygen saturation as useful clinical measures to identify patients at risk for critical care.


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Last updated on 2022-07-04 at 18:19