A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Advances in Surface Biofunctionalization and Intelligent Monitoring of Vascular Scaffolds
Tekijät: Rafique, Muhammad; Ali, Onaza; Niazi, Muhammad Shehr Yar Ali Khan; Zhang, Jialing; Shafiq, Muhammad; Fang, Jun
Julkaisuvuosi: 2026
Lehti: Research
Artikkelin numero: 1182
Vuosikerta: 9
ISSN: 2096-5168
eISSN: 2639-5274
DOI: https://doi.org/10.34133/research.1182
Julkaisun avoimuus kirjaamishetkellä: Avoimesti saatavilla
Julkaisukanavan avoimuus : Kokonaan avoin julkaisukanava
Verkko-osoite: https://doi.org/10.34133/research.1182
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/509023603
Rinnakkaistallenteen lisenssi: CC BY
Rinnakkaistallennetun julkaisun versio: Kustantajan versio
Vascular scaffolds are fundamental devices in treating vascular occlusions, aneurysms, and hemodialysis access. However, their long-term efficacy is often compromised by 2 major pathophysiological responses: acute thrombosis and intimal hyperplasia, underscoring the need for effective antithrombotic treatment and intensive surveillance. This review highlights the emerging approaches used to address such challenges in vascular scaffolds: surface biofunctionalization and intelligent monitoring systems. We first introduce the leading biodegradable elastic polymers for vascular scaffolds, followed by a comprehensive overview of surface biofunctionalization techniques for preventing thrombosis and promoting endothelialization. The review further explores the cutting-edge advances in integrating flexible bioelectronics with cardiovascular implants for intelligent real-time monitoring of hemodynamics, thrombosis, and restenosis. It concludes with a discussion of the remaining challenges and future perspectives, thereby promoting the development of more effective cardiovascular therapies and their clinical applications.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
Julkaisussa olevat rahoitustiedot:
This work was supported by the National Natural Science Foundation of China (32271402), Shanghai Pujiang Program (22PJ1405100), and "Star of Jiao Tong University" Program of Medical and Industrial Cross-Research Fund (24X010301418, 25X010301345), Shanghai Post-doctoral Excellence Program (2024272). This work was partially supported by the European Union's Horizon Europe research and innovation programme under Marie Sklodowska-Curie grant agreement [101126611]. M.R. is a Post-doctoral Research Fellow at the Department of Biomedical Engineering, Shanghai Jiao Tong University, China.
