Perfluorohexyloctane: More than Meets the Eye?




Alijagic, Andi; Oresic, Matej; Hyötyläinen, Tuulia

PublisherAmerican Chemical Society (ACS)

2026

 Chemical Research in Toxicology

acs.chemrestox.5c00507

39

2

205

207

0893-228X

1520-5010

DOIhttps://doi.org/10.1021/acs.chemrestox.5c00507

https://doi.org/10.1021/acs.chemrestox.5c00507

https://research.utu.fi/converis/portal/detail/Publication/509005127



Perfluorohexyloctane (F6H8) is a semifluorinated alkane increasingly used in medical applications. Emerging evidence, however, indicates that this compound can persist in biological systems and influence cellular processes. These observations suggest that the exceptional stability of F6H8, while beneficial for medical performance, may also have implications for long-term biological and health outcomes.


The authors acknowledge the "Investigation of endocrine-disrupting chemicals as contributors to progression of metabolic dysfunction-associated steatotic liver disease" (EDC-MASLD) consortium funded by the Horizon Europe Program of the European Union under Grant Agreement 101136259. Views and opinions expressed are those of the author(s) only and do not necessarily reflect those of the European Union. Neither the European Union nor the granting authority can be held responsible for them.


Last updated on 04/03/2026 01:50:39 PM