A1 Refereed original research article in a scientific journal
Pain Management in Aneurysmatic Subarachnoid Haemorrhage: A Survey of Nordic Physicians
Authors: Sariola, Hanna; Kalliomäki, Maija‐Liisa; Kiiski, Heikki; Raatikainen, Essi; Frösen, Juhana; Reinikainen, Matti; Savioja, Hanna; Møller, Kirsten; Lohela, Terhi; Takala, Riikka; Sigurdsson, Martin; Romundstad, Luis; Dyrskog, Stig; Bülow, Karsten; Hästbacka, Johanna
Publisher: Wiley
Publication year: 2026
Journal: Acta Anaesthesiologica Scandinavica
Article number: e70194
Volume: 70
Issue: 3
ISSN: 0001-5172
eISSN: 1399-6576
DOI: https://doi.org/10.1111/aas.70194
Publication's open availability at the time of reporting: Open Access
Publication channel's open availability : Partially Open Access publication channel
Web address : https://doi.org/10.1111/aas.70194
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/508964213
Self-archived copy's licence: CC BY NC ND
Self-archived copy's version: Publisher`s PDF
Background
Headache caused by aneurysmatic subarachnoid hemorrhage (aSAH) is often severe and may persist long after the ictus. Pharmacological pain management can be challenging due to poor efficacy or adverse effects. Multimodal pharmacotherapy is often required. Lack of guidelines and good quality clinical studies on pain management has led to variation in pain management practices. Knowledge of current practice and goals of pain management in Nordic countries is lacking. We aimed to fill these knowledge gaps by conducting a survey targeting Nordic clinicians involved in aSAH treatment.
MethodsAn electronic survey in English was sent to national coordinators in December 2023. The coordinators distributed the survey to intensivists, neurosurgeons, and other specialists treating aSAH patients in their respective countries. The survey contained 63 questions gathering background information, current aSAH pain management during the hospital stay and at hospital discharge, follow-up, and preferred outcome measures regarding a clinical trial on pain management in aSAH. The results were analysed and presented descriptively.
ResultsWe received 70 responses: 36 from Finland, 11 from Norway, 11 from Denmark, 5 from Sweden and 7 from Iceland. Respondents were intensivists (N = 46), neurosurgeons (N = 20), neurologists (N = 2), and others (N = 2). The most frequently used pain medications at ICUs were paracetamol, opioids, and non-steroidal anti-inflammatory drugs (NSAID). Most neurosurgeons (70%, N = 14) responded that they never prescribe opioids at hospital discharge for aSAH patients. The most preferred outcome for a clinical trial was patients' self-reported quality of life.
ConclusionsIn the Nordic countries, paracetamol, opioids, and NSAIDs were reported as the most frequently used analgesics in the management of aSAH related pain in the ICU. Use of gabapentinoids was commonly reported by Danish respondents, unlike respondents from other Nordic countries. Neurosurgeons reported that they rarely prescribe opioids at hospital discharge.
Editorial CommentThis survey of Nordic clinicians involved in ICU and neurosurgical management of subarachnoid bleed (aneurysm) cases presents preferences for pain management in hospital and with discharge, as well as assessing clinician preferences for outcomes by which to assess pain management in these cases.
Downloadable publication This is an electronic reprint of the original article. |
Funding information in the publication:
This work was supported by Suomen Anestesiologiyhdistys; State funding for university-level health research, Tampere University Hospital, Wellbeing services county of Pirkanmaa, Project number T63804.