A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Global, regional, and national burden of headache disorders, 1990–2021, with forecasts to 2050: A Global Burden of Disease study 2021
Tekijät: GBD 2021 Headache Collaborators
Kustantaja: Elsevier BV
Julkaisuvuosi: 2025
Lehti: Cell Reports Medicine
Artikkelin numero: 102348
Vuosikerta: 6
Numero: 10
ISSN: 2666-3791
DOI: https://doi.org/10.1016/j.xcrm.2025.102348
Julkaisun avoimuus kirjaamishetkellä: Avoimesti saatavilla
Julkaisukanavan avoimuus : Kokonaan avoin julkaisukanava
Verkko-osoite: https://doi.org/10.1016/j.xcrm.2025.102348
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/508240517
Rinnakkaistallenteen lisenssi: CC BY
Rinnakkaistallennetun julkaisun versio: Kustantajan versio
Headache disorders, especially migraines and tension-type headaches (TTHs), are major global public health concerns, as shown by the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021. We provide updated global estimates of prevalence and years lived with disability (YLDs) from 1990 to 2021 across 204 countries and territories and forecasts through 2050. In 2021, there are 2.0 billion people with TTH and 1.2 billion with migraine. Although TTH is more prevalent, migraine causes higher disability. While crude prevalence and YLDs increased, age-standardized rates remained stable and are projected to continue this trend due to population growth. There is a disproportionately higher burden in women aged 30-44 and countries with higher Socio-demographic Index and Healthcare Access and Quality Index. Despite this, migraines remain underrecognized in health policies and funding. This study emphasizes the urgent need to prioritize headache disorders in global health agendas.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
Julkaisussa olevat rahoitustiedot:
This study was funded by the Bill and Melinda Gates Foundation (OPP1152504); the Australian National Health and Medical Research Council; and the Queensland Department of Health, Australia. The Yonsei Fellowship, funded by Youn Jae Lee (to J.I.S.), also supported this work. This work was supported by the Institute of Information & Communications Technology Planning & Evaluation (IITP) grant funded by the Korean government (RS-2024-00509257 [Global AI Frontier Lab] to D.K.Y.). This work was supported by the Institute of Information & communications Technology Planning & Evaluation (IITP) grant funded by the Korean government (2022-0-00621 or RS-2022-II220621 [Development of artificial intelligence technology that provides dialog-based multi-modal explainability] to T.J.S.). This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (RS-2023-00262087 to T.J.S. and RS-2025-02220492 to D.K.Y.). This research was supported by a grant from the National Research Foundation of Korea (NRF), funded by the Korean government (MSIT) (2022R1A2C1091767 to M.K.C.). This research was supported by the BK21 FOUR (Fostering Outstanding Universities for Research) funded by the Ministry of Education (MOE, Korea) and National Research Foundation of Korea (NRF-5199990614253 to T.-J.S., Education Research Center for 4IR-Based Health Care). The study’s funder had no role in the study design, data collection, data analysis, data interpretation, or writing of the report. All authors had full access to the study data and had final responsibility for the decision to submit the manuscript for publication.
