A1 Refereed original research article in a scientific journal
Partition Coefficients (logP) of Hydrolysable Tannins
Authors: Valtteri Virtanen, Maarit Karonen
Publisher: MDPI
Publication year: 2020
Journal: Molecules
Journal name in source: MOLECULES
Journal acronym: MOLECULES
Article number: ARTN 3691
Volume: 25
Issue: 16
Number of pages: 16
eISSN: 1420-3049
DOI: https://doi.org/10.3390/molecules25163691
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/50375115
Abstract
The partition coefficients (logP) betweenn-octanol and water of 47 purified and characterized hydrolysable tannins were measured with the shake flask method utilizing UPLC and HPLC with UV detection. Results show that galloyl glucoses and gallotannins are clearly more hydrophobic than ellagitannins but the differences in hydrophobicity within ellagitannins are more varied than within galloyl glucoses or gallotannins. Most notable structural features that were found to influence the hydrophobicity of ellagitannins were the number of free galloyl groups, acyclic versus cyclic polyol, substitution of the anomeric position of glucose and(4)C(1)versus(1)C(4)conformation of the glucopyranose core.
The partition coefficients (logP) betweenn-octanol and water of 47 purified and characterized hydrolysable tannins were measured with the shake flask method utilizing UPLC and HPLC with UV detection. Results show that galloyl glucoses and gallotannins are clearly more hydrophobic than ellagitannins but the differences in hydrophobicity within ellagitannins are more varied than within galloyl glucoses or gallotannins. Most notable structural features that were found to influence the hydrophobicity of ellagitannins were the number of free galloyl groups, acyclic versus cyclic polyol, substitution of the anomeric position of glucose and(4)C(1)versus(1)C(4)conformation of the glucopyranose core.
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