A1 Refereed original research article in a scientific journal
Combining mental health and climate-smart agricultural interventions to improve food security in humanitarian settings: study protocol for the THRIVE cluster-randomized controlled trial with mothers in Nakivale refugee settlement, Uganda
Authors: Hall, Jonathan; Ainamani, Herbert E.; Vassiliou, Phaidon T. B.; Döring, Stefan; Gredebäck, Gustaf; Peltonen, Kirsi; Scharpf, Florian; Sen, Umay; Sutter, Matthias; Walsh, James I.; Hecker, Tobias
Publisher: BioMed Central
Publication year: 2025
Journal: Trials
Article number: 331
Volume: 26
eISSN: 1745-6215
DOI: https://doi.org/10.1186/s13063-025-09042-y
Publication's open availability at the time of reporting: Open Access
Publication channel's open availability : Open Access publication channel
Web address : https://doi.org/10.1186/s13063-025-09042-y
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/500139613
Background
Climate extremes in Africa threaten the food security of war-affected refugees, who often experience mental health challenges that hinder their capacity for agricultural adaptation. Cost-effective, climate-smart farming interventions are crucial for addressing food insecurity in humanitarian contexts, yet evidence on their effectiveness is limited, and the potential benefits of integrating them with mental health interventions remain unexplored. We hypothesize that the success of agricultural interventions, especially under adversity, is influenced by mental health and psychological functioning.
MethodsThis study employs a three-arm, parallel-group, cluster-randomized controlled trial (cRCT) in the Nakivale refugee settlement, Uganda. Thirty villages within the settlement will be randomized in a 1:1:1 allocation ratio to one of three conditions: Enhanced Usual Care, a Home Gardening Intervention (HGI) or HGI combined with the peer-delivered psychosocial intervention Self-Help Plus (SH + HGI). A total of 900 refugee mothers and their children (aged 3–4 years) will be enrolled, with 30 dyads per village. The primary outcome is food insecurity at 12 months post-intervention, assessed using the Food Insecurity Experience Scale (FIES). Secondary outcomes include dietary diversity, child malnutrition and mothers’ psychological distress. Data will be collected at baseline, 3-month and 12-month follow-ups. Primary analyses will use an intention-to-treat (ITT) approach.
DiscussionThis study will shed light on the role of mental health in agricultural adaptation for food security, evaluating the efficacy of scalable, cost-effective interventions in a refugee setting. The findings will have implications for the design and implementation of integrated food security and mental health programs in humanitarian and other resource-constrained settings.
Downloadable publication This is an electronic reprint of the original article. |
Funding information in the publication:
Open access funding provided by Uppsala University. This work is supported by FORMAS (grant no. 2022–01573).