A2 Refereed review article in a scientific journal
Utility of Ureteric Jets as an Adjuvant Diagnostic Modality in Children with Ureteropelvic Junction Obstruction: A Systematic Review and Meta-analysis
Authors: Prasad, Gaurav; Agarwal, Keshav; Gulia, Annu; Pakkasjärvi, Niklas; Ranjan, Abhishek; Jana, Manisha; Yadav, Devendra Kumar; Anand, Sachit
Publisher: Ovid Technologies (Wolters Kluwer Health)
Publication year: 2025
Journal: Journal of Indian Association of Pediatric Surgeons
Volume: 30
Issue: 5
First page : 569
Last page: 575
ISSN: 0971-9261
eISSN: 1998-3891
DOI: https://doi.org/10.4103/jiaps.jiaps_72_25
Publication's open availability at the time of reporting: Open Access
Publication channel's open availability : Open Access publication channel
Web address : https://doi.org/10.4103/jiaps.jiaps_72_25
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/499988028
Background: Ureteropelvic junction obstruction (UPJO) is a common cause of pediatric hydronephrosis, yet only one-Third of affected children require surgery. Differentiating obstructive from non-obstructive cases remains challenging with current imaging methods. This systematic review and meta-Analysis evaluated the role of ureteric jets, assessed via color Doppler ultrasonography (USG), as an adjuvant diagnostic modality to complement gray-scale USG in children with UPJO.
Materials and Methods: A systematic search of PubMed, Embase, Scopus, and Web of Science databases was conducted to identify studies reporting on ureteric jet frequency (UJF) in UPJO. Standardized mean difference (SMD) with 95% confidence intervals (CI) was calculated for the pooled data, while the I² statistic assessed heterogeneity. Methodological quality was evaluated using the Newcastle-Ottawa scale. Results: Five studies (111 patients) met inclusion criteria. Ureteric jets were absent in 67.3% of UPJO cases, with diagnostic accuracy reaching 94%. Meta-Analysis revealed a significant reduction in UJF in obstructed kidneys (SMD =-2.01, 95% CI:-3.09 to-0.94, P = 0.0002), though heterogeneity was substantial (I² = 80%, P = 0.006). The methodological quality of the included studies was good in four studies and poor in one study. Conclusions: The current systematic review demonstrated the absence of ureteric jets and a significant
reduction in the UJF in the obstructed kidneys. However, due to heterogeneity among the included studies, further studies are needed to standardize the protocols before any definite conclusions are drawn.
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