A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Generation of two human induced pluripotent stem cell lines from peripheral blood mononuclear cells featuring normal or mutated STAB1 gene
Tekijät: Sandelin, Sanne; Giannareas, Nikolaos; Kere, Juha; Seppänen, Mikko R. J.; Hollmen, Maija; Närvä, Elisa
Kustantaja: Elsevier
Kustannuspaikka: AMSTERDAM
Julkaisuvuosi: 2025
Journal: Stem Cell Research
Tietokannassa oleva lehden nimi: STEM CELL RESEARCH
Lehden akronyymi: STEM CELL RES
Artikkelin numero: 103750
Vuosikerta: 87
Sivujen määrä: 5
ISSN: 1873-5061
eISSN: 1876-7753
DOI: https://doi.org/10.1016/j.scr.2025.103750
Verkko-osoite: https://doi.org/10.1016/j.scr.2025.103750
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/498990284
Here, we report the establishment of a human induced pluripotent stem cell (hiPSC) line TUR-STAB1-B1 derived from peripheral blood mononuclear cells of a patient carrying heterozygous mutations 52,509,890 C>A 790L>I and 52,520,515 G>A 1872R>H on STAB1 gene in addition to a normal control cell line TUR-B1. The pluripotency, identity, quality, safety, and sequence of the mutation sites of the cell lines were confirmed. The generated patient-specific cell line will facilitate detailed studies of the STAB1 in various differentiated cell types.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
Julkaisussa olevat rahoitustiedot:
This work was supported by funding from ImmuDocs (Finnish National Doctoral Education Pilot), BioCity Turku Funding, Finland; Finnish Red Cross Blood Service, Finland; Sigrid Jusélius Foundation, Finland; Drug Research Doctoral Programme (DRDP), InFlames, The Foundation for Pediatric Research, Pediatric Research Center HUS Helsinki University Hospital Research Funds, Finland; and Emil Aaltonen Foundation, Finland.
