A2 Refereed review article in a scientific journal
Implications of plastic-derived endocrine disruptors on human health
Authors: Ojo, Adebola Busola; Agbeye, Oluwatobi Deborah; Ogwa, Theophilus Oghenenyoreme; Adedoyin, Damilola; Rotimi, Damilare Emmanuel; Ojo, Oluwafemi Adeleke
Publisher: TAYLOR & FRANCIS LTD
Publishing place: ABINGDON
Publication year: 2025
Journal: Toxicology Mechanisms and Methods
Journal name in source: TOXICOLOGY MECHANISMS AND METHODS
Journal acronym: TOXICOL MECH METHOD
Number of pages: 25
ISSN: 1537-6516
eISSN: 1537-6524
DOI: https://doi.org/10.1080/15376516.2025.2510525
Web address : https://doi.org/10.1080/15376516.2025.2510525
Endocrine-disrupting chemicals (EDCs), such as bisphenol A (BPA), bisphenol S (BPS), phthalates, and micro- and nanoplastics, present substantial environmental and health hazards because of their potential to disrupt hormonal systems. Micro- and nanoplastics can release EDCs that disrupt reproductive and developmental processes, potentially affecting future generations. BPA, a common plasticizer and resin component, mimics estrogen and disrupts thyroid hormone metabolism, contributing to obesity, diabetes, and cardiovascular issues. BPS, a BPA substitute, exhibits similar endocrine-disrupting properties and persists longer in the environment. Phthalates, which are widely used as plasticizers, are associated with reproductive issues, metabolic conditions, and developmental issues in children. Combined exposure to multiple EDCs can amplify health risks, underscoring the need for further research on the synergistic impacts of these chemicals. This review underscores the urgent need for effective regulatory measures and further investigations into the health impacts of EDCs to mitigate their harmful impacts on the health of humans and the environment.
Funding information in the publication:
The author(s) reported there is no funding associated with the work featured in this article.
