This paper synthesizes the latest design knowledge accumulated with the Comicubes service design tool and solution prototyping method, and shares some of the lessons learned during the multiple workshops organized. The physical prototyping tool combines two-dimensional sketching with a three-dimensional and open-ended play medium – the cube. The method incorporates key aspects of service-oriented interaction design. We have used Comicubes to facilitate co-creation to generate new ideas, solutions or approaches to various design challenges related to the gamification, toyification and playification of services. This study summarizes four case studies where Comicubes has been employed as a platform for 3D prototyping, testing, and simultaneously, a tool to stimulate, envision and co-create interactive user experiences. The findings of the four case studies summarized indicate that the Comicubes tool and method are suitable to be used in design processes interested to facilitate co-creation and innovation of products, services and experiential spaces.