A1 Refereed original research article in a scientific journal

Light Cigarette Smoking Increases Risk of All-Cause and Cause-Specific Mortality: Findings from the NHIS Cohort Study




AuthorsQin W, Magnussen CG, Li SX, Steffen LM, Xi B, Zhao M

PublisherMDPI

Publication year2020

JournalInternational Journal of Environmental Research and Public Health

Journal name in sourceINTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH

Journal acronymINT J ENV RES PUB HE

Article numberARTN 5122

Volume17

Issue14

Number of pages10

eISSN1660-4601

DOIhttps://doi.org/10.3390/ijerph17145122

Web address https://doi.org/10.3390/ijerph17145122

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/49464611


Abstract
Very few studies have examined the association between light cigarette smoking (i.e., <= 5 cigarettes per day) and mortality. The aim of this study was to examine the association of light cigarette smoking with all-cause and cause-specific mortality among adults in the United States. Data were from 13 waves of the National Health Interview Survey (1997 to 2009) that were linked to the National Death Index records through December 31, 2011. A total of 329,035 participants aged >= 18 years in the United States were included. Deaths were from all cause, cancer, cardiovascular disease (CVD) and respiratory disease and were confirmed by death certification. During a median follow-up of 8.2 years, 34,862 participants died, of which 8415 were from cancer, 9031 from CVD, and 2040 from respiratory disease. Compared with never-smokers, participants who smoked 1-2 (hazard ratios (HR) = 1.94, 95%CI = 1.73-2.16) and 3-5 cigarettes (HR = 1.99, 1.83-2.17) per day were at higher risk of all-cause mortality after adjustment for demographic variables, lifestyle factors and physician-diagnosis of chronic disease. The associations were stronger for respiratory disease-specific mortality, followed by cancer-specific mortality and CVD-specific mortality. For example, the HRs (95% CIs) of smoking 1-2 cigarettes per day were 9.75 (6.15-15.46), 2.28 (1.84-2.84) and 1.93 (1.58-2.36), respectively, for these three cause-specific mortalities. This study indicates that light cigarette smoking increases risk of all-cause and cause-specific mortality in US adults.

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