Background: Nursing applicants need realistic information about the nursing profession to make an informed career choice.

Aim: to develop the 360°VLE (Virtual Learning Environment) and evaluate its effect on nursing applicants’ perception of the nursing profession.

Methods: The quasi-experimental intervention (360°VLE) study was implemented as part of the nursing education entrance examination. Before the entrance examination, nursing applicants (n = 1115) in the intervention (n = 450) and control group (n = 665) received entrance exam invitation letters with and without an access link to the platform, respectively. The applicants’ perception of the nursing profession was measured using the Perception of Nursing Profession Instrument. Data were analyzed with multiple linear regression.

Results: The use of 360°VLE has a significant effect on nursing education applicants’ perception of the nursing profession. In addition, having a previous healthcare-related work history and seeking information about the profession from nurses are significantly correlated with more correct perception of the profession.

Conclusions: 360°VLE is a viable solution for improving nursing applicants’ perception of the nursing profession.