A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Application of bacteriophages in sensor development
Tekijät: Peltomaa R, Lopez-Perolio I, Benito-Pena E, Barderas R, Moreno-Bondi MC
Kustantaja: SPRINGER HEIDELBERG
Julkaisuvuosi: 2016
Lehti:: Analytical and Bioanalytical Chemistry
Tietokannassa oleva lehden nimi: ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Lehden akronyymi: ANAL BIOANAL CHEM
Vuosikerta: 408
Numero: 7
Aloitussivu: 1805
Lopetussivu: 1828
Sivujen määrä: 24
ISSN: 1618-2642
DOI: https://doi.org/10.1007/s00216-015-9087-2
Tiivistelmä
Bacteriophage-based bioassays are a promising alternative to traditional antibody-based immunoassays. Bacteriophages, shortened to phages, can be easily conjugated or genetically engineered. Phages are robust, ubiquitous in nature, and harmless to humans. Notably, phages do not usually require inoculation and killing of animals; and thus, the production of phages is simple and economical. In recent years, phage-based biosensors have been developed featuring excellent robustness, sensitivity, and selectivity in combination with the ease of integration into transduction devices. This review provides a critical overview of phage-based bioassays and biosensors developed in the last few years using different interrogation methods such as colorimetric, enzymatic, fluorescence, surface plasmon resonance, quartz crystal microbalance, magnetoelastic, Raman, or electrochemical techniques.
Bacteriophage-based bioassays are a promising alternative to traditional antibody-based immunoassays. Bacteriophages, shortened to phages, can be easily conjugated or genetically engineered. Phages are robust, ubiquitous in nature, and harmless to humans. Notably, phages do not usually require inoculation and killing of animals; and thus, the production of phages is simple and economical. In recent years, phage-based biosensors have been developed featuring excellent robustness, sensitivity, and selectivity in combination with the ease of integration into transduction devices. This review provides a critical overview of phage-based bioassays and biosensors developed in the last few years using different interrogation methods such as colorimetric, enzymatic, fluorescence, surface plasmon resonance, quartz crystal microbalance, magnetoelastic, Raman, or electrochemical techniques.
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