A1 Refereed original research article in a scientific journal
Platelet-rich plasma does not influence magnetic resonance imaging findings of the gluteus muscles after total hip arthroplasty through the Hardinge approach
Authors: Nieminen, Anette; Nurminen, Janne; Aavikko, Anni; Puhakka, Jani; Haapala, Jussi; Keemu, Hannes; Kukkonen, Juha; Alho, Ari; Uusalo, Panu; Makela, Keijo; Kosola, Jussi
Publisher: SPRINGER
Publishing place: NEW YORK
Publication year: 2025
Journal: Skeletal Radiology
Journal name in source: SKELETAL RADIOLOGY
Journal acronym: SKELETAL RADIOL
Number of pages: 10
ISSN: 0364-2348
eISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-025-04876-8
Web address : https://doi.org/10.1007/s00256-025-04876-8
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/485058241
Objective
Total hip arthroplasty through the Hardinge approach damages the hip abductor muscles. MRI can be used to assess adverse postoperative events. In this prospective randomized controlled trial, we evaluated MRI findings and whether platelet-rich plasma affected postoperative healing of the gluteal muscles (gluteus medius and minimus).
Materials and methods
Forty patients with hip osteoarthritis requiring treatment with total hip arthroplasty, aged between 60 and 76 years, were included. Patients were randomized into two groups: 19 patients in the platelet-rich plasma group and 21 in the placebo group. Platelet-rich plasma or placebo was injected into the gluteus medius tendon incision line during closure. Postoperative hip MRI and plain radiographs were taken 3 and 12 months after surgery.
Results
MRI showed fatty atrophy of the gluteal muscles in all 40 patients (100%), gluteal muscle tear in 11 patients (28%), and atrophy in 16 patients (40%) at both 3 and 12 months postoperatively. Fluid collections related to the operated hip joint were seen in 18 patients (45%) at 3 months and 13 patients (33%) at 12 months, heterotopic ossification formation in nine patients (23%) at 3 months, and 12 patients (31%) at 12 months. There were no significant differences in imaging findings between the two groups.
Conclusion
MRI can be a valuable tool for evaluating postoperative healing after total hip arthroplasty. Fatty atrophy of the gluteal muscles was a common finding. Platelet-rich plasma injection into the gluteus medius tendon did not improve healing detected by MRI.
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Funding information in the publication:
Open Access funding provided by University of Turku (including Turku University Central Hospital).