Fixed partial dentures (FPD) fabricated from FRC (hereafter abbreviated as FRC FPDs) are nowadays considered a minimally invasive and cost-effective treatment1,2. They gained popularity in the early 1990’s and since then have been commonly used in teeth with poor prognosis, as a substitute for removable partial dentures that replace a few missing teeth and in situations where costs are an issue3 . Clinical experience has shown that most clinical failures are due to three main reasons: incorrect fiber orientation4 , incorrectly designed fiber framework5,6 or inaccurate occlusal adjustment3 . The most commonly reported reasons for FRC FPD failures are delamination and chipping of the veneering composite2,5,7–10, dislodgement4,8,9, and partial6 or complete debonding. Traditionally FRC FPDs have been fabricated directly (intraorally), semi-directly (chairside i.e. pre-making the fiber framework and the pontic partially extraorally)2,5,7 or indirectly (in a dental laboratory)3,4,6,8,9,11. Until today, CAD/CAM technology has been used only in vitro for fabricating the pontic of a simple FRC FPD12,13. To the authors’ knowledge, this technique, has not been yet implemented clinically.