A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Prescribing patterns before the initiation of novel antidiabetic medicines in public, occupational, and private healthcare: a register study reflecting the guidelines of care in type 2 diabetes




TekijätRättö, Hanna; Nurminen, Mikko; Aaltonen, Katri

KustantajaSpringer Science and Business Media LLC

Julkaisuvuosi2024

Lehti: BMC Health Services Research

Tietokannassa oleva lehden nimiBMC Health Services Research

Lehden akronyymiBMC Health Serv Res

Artikkelin numero1553

Vuosikerta24

Numero1

ISSN1472-6963

eISSN1472-6963

DOIhttps://doi.org/10.1186/s12913-024-12010-y

Julkaisun avoimuus kirjaamishetkelläAvoimesti saatavilla

Julkaisukanavan avoimuus Kokonaan avoin julkaisukanava

Verkko-osoitehttps://doi.org/10.1186/s12913-024-12010-y

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/477191526


Tiivistelmä

BACKGROUND

Disparities in access to healthcare has been implied before in Finland, a country with universal healthcare but de facto tiered primary care. Less is however known about the content of care provided in different settings. Previous studies indicate potential disparities in prescribing newer medicines between healthcare sectors. We compared the preceding prescribing patterns of patients who initiated a sodium-glucose co-transporter 2 (SGLT2) inhibitor or a glucagon-like peptide-1 (GLP-1) analogue in public, occupational, and private healthcare.

METHODS

We used logistic models and patient-level register data from the city of Oulu, Finland, during 2014-2018. Among patients who initiated SGLT2 inhibitors or GLP-1 analogues, we studied whether it was a first-line treatment or if other antidiabetic medicines preceded the use. In addition, prior use of statins (a lipid-lowering medicine) and insulins were studied. Clinical guidelines for type 2 diabetes recommend in most cases metformin in first-line, and insulin only at later stages or in case of severe hyperglycaemia. Using a lipid-lowering medicine is typically recommended for all.

RESULTS

The examined novel antidiabetic medicines were seldom initiated in first-line, and no significant differences were observed for preceding statin use across sectors, net of patient characteristics. However, patients in the public sector were more likely to have used insulin previously compared to patients in occupational sector.

CONCLUSIONS

Before the initiation of the examined novel antidiabetic medicines, no marked differences across sectors in the use of other antidiabetic medicines or statins were observed. The higher likelihood of prior insulin use in the public sector might reflect initiation at a later stage and/or unobserved differences in clinical characteristics across patient populations.


Ladattava julkaisu

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.




Julkaisussa olevat rahoitustiedot
This study was funded by the Social Insurance Institution of Finland (Kela), grant number 2/26/2021 (MN.)
The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


Last updated on 2025-15-08 at 15:35