A1 Refereed original research article in a scientific journal

Standardized List Evaluating Apnea (SLEAP): A Comprehensive Survey to Define the Quality of Life in OSA




AuthorsAbdelwahab, Mohamed; Saltychev, Mikhail; Lechner, Matt; Adibi, Elahe; Wadsworth, Elizabeth Walker; Fleury, Thomaz; Rakha, Abdelwahab; Khafagy, Yasser; Abdelfattah, Ahmed; Al-Sayed, Ahmed A.; Chou, Courtney; Ali, Ban; Liu, Stanley; Kushida, Clete; Capasso, Robson

PublisherWILEY

Publishing placeHOBOKEN

Publication year2025

JournalOtolaryngology - Head and Neck Surgery

Journal name in sourceOTOLARYNGOLOGY-HEAD AND NECK SURGERY

Journal acronymOTOLARYNG HEAD NECK

Volume172

Issue2

First page 668

Last page677

Number of pages10

ISSN0194-5998

eISSN1097-6817

DOIhttps://doi.org/10.1002/ohn.1072

Web address https://doi.org/10.1002/ohn.1072


Abstract

Objective
To develop and validate a patient-reported outcome measure (PROM) to evaluate the quality of life (QoL) among patients with obstructive sleep apnea (OSA).

Study Design
A prospective cohort study.

Settings
Tertiary referral center.

Methods
We developed a 15-item English questionnaire that was administered to 176 adults with OSA and 22 adult controls without symptoms of OSA in a tertiary sleep surgery clinic between June 2021 and December 2021. The internal consistency and test-retest reliability were measured using the Cronbach's α and the intraclass correlation coefficient, respectively. The 2-sample Wilcoxon rank-sum (Mann-Whitney) test was applied to compare the 2 groups. Convergent validity of the test scores of the questionnaire was compared to previously validated outcome measures and objective sleep study outcomes using the Spearman correlation coefficient.

Results
Of the 198 respondents (176 cases and 22 controls); 71% were men and 29% were women. The internal consistency was excellent with the α of .92 (lower 95% confidence limit of 0.90). All the test-retest correlations were positive, significant, and strong ranging from 0.50 to 0.90. The differences between cases and controls were statistically significant for all the items and for the total score. The total score of the questionnaire with the Epworth Sleepiness Scale and objective OSA measures was moderate to strong.

Conclusions and Relevance
The new tool provides a validated PROM to evaluate the QoL among OSA patients specifically, with excellent internal consistency, reasonable test-retest reliability, discriminant validity, and construct validity.

Level of Evidence
Level 4.



Last updated on 2025-27-03 at 08:37