A4 Vertaisarvioitu artikkeli konferenssijulkaisussa
Study of Repeatability of a Novel PET Flow Phantom
Tekijät: R. Siekkinen, J. Teuho, A. K. Kirjavainen, K. Koskensalo, A. Saraste, M. Teräs
Konferenssin vakiintunut nimi: IEEE Nuclear Science Symposium and Medical Imaging Conference
Kustantaja: Institute of Electrical and Electronics Engineers Inc.
Julkaisuvuosi: 2020
Journal: IEEE Nuclear Science Symposium and Medical Imaging Conference record
Kokoomateoksen nimi: 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
Tietokannassa oleva lehden nimi: 2019 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2019
ISBN: 978-1-7281-4165-7
eISBN: 978-1-7281-4164-0
ISSN: 1091-0026
DOI: https://doi.org/10.1109/NSS/MIC42101.2019.9060065
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/47374723
Dynamic Positron Emission Tomography (PET) is a valuable method in
Myocardial Perfusion Imaging (MPI) allowing quantification of blood flow
in the myocardial tissue. A reference test object simulating myocardial
blood flow is needed. A newly developed PET phantom enables flow
quantification with a known reference. However, the repetability of the
flow phantom needs to be confirmed.
The aim of this study was to confirm
that no significant variability exists between image-derived or
reference flow between subsequent measurements. Finally, we confirmed
repeatability of the flow values derived by kinetic modelling from PET
images of the phantom.
Five repeated measurements with fixed acquisition
and reconstruction protocol were performed. PET images were analysed
with a software provided by the phantom vendor to derive the
time-activity curves for modelling of flow values.
The image-derived
flow rates varied with SD of 0.89 mL/min and 0.86 mL/min between
subsequent measurements. Error between image-derived and reference flow
was less than 5.5 % on average within all subsequent repeats.
Fluctuations between the subsequent measurements are considered to arise
from the dose administration and water flow inside the phantom.
In
conclusion, the newly developed PET flow phantom shows high
repeatability and is a reliable platform for quality control and
validation studies in MPI in PET.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
