A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Effect of bioactive glass air-abrasion on the wettability and osteoblast proliferation on sandblasted and acid-etched titanium surfaces

Julkaisun tekijät: Abushahba Faleh, Tuukkanen Juha, Aalto‐Setälä Laura, Miinalainen Ilkka, Hupa Leena, Närhi Timo O

Kustantaja: WILEY

Julkaisuvuosi: 2020

Journal: European Journal of Oral Sciences

Tietokannassa oleva lehden nimi: EUROPEAN JOURNAL OF ORAL SCIENCES

Lehden akronyymi: EUR J ORAL SCI

Volyymi: 128

Julkaisunumero: 2

Sivujen määrä: 10

ISSN: 0909-8836

eISSN: 1600-0722

DOI: http://dx.doi.org/10.1111/eos.12683

Verkko-osoite: https://onlinelibrary.wiley.com/doi/10.1111/eos.12683

The aim of this study was to evaluate the hydrophilicity, surface free energy, and proliferation and viability of human osteoblast-like MC3T3-E1 cells on sandblasted and acid-etched titanium surfaces after air-abrasion with 45S5 bioactive glass, zinc-containing bioactive glass, or inert glass. Sandblasted and acid-etched titanium discs were subjected to air-abrasion with 45S5 bioactive glass, experimental bioactive glass (Zn4), or inert glass. Water contact angles and surface free energy were evaluated. The surfaces were studied with preosteoblastic MC3T3-E1 cells. Air-abrasion with either type of glass significantly enhanced the hydrophilicity and surface free energy of the sandblasted and acid-etched titanium discs. The MC3T3-E1 cell number was higher for substrates air-abraded with Zn4 bioactive glass and similar to that observed on borosilicate coverslips (controls). Confocal laser scanning microscopy images showed that MC3T3-E1 cells did not spread as extensively on the sandblasted and acid-etched and bioactive glass-abraded surfaces as they did on control surfaces. However, for 45S5- and Zn4-treated samples, the cells spread most at the 24 h time point and changed their morphology to more spindle-like when cultured further. Air-abrasion with bioactive glass and inert glass was shown to have a significant effect on the wettability and surface free energy of the surfaces under investigation. Osteoblast cell proliferation on sandblasted and acid-etched titanium discs was enhanced by air-abrasion with 45S5 bioactive glass and experimental Zn4 bioactive glass compared with air-abrasion with inert glass or no air-abrasion.

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Last updated on 2021-11-08 at 09:02