A1 Refereed original research article in a scientific journal
Prevalence of Pertactin-Deficient Bordetella pertussis Isolates, Slovenia
Authors: Barkoff, Alex-Mikael; Kastrin, Tamara; Seme, Katja; Vitek, Marta Grgič; Mertsola, Jussi; He, Qiushui
Publisher: Centers for Disease Control and Prevention (CDC)
Publication year: 2024
Journal: Emerging Infectious Diseases
Journal name in source: Emerging Infectious Diseases
Volume: 30
Issue: 11
ISSN: 1080-6040
eISSN: 1080-6059
DOI: https://doi.org/10.3201/eid3011.231393
Web address : http://doi.org/10.3201/eid3011.231393
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/470941132
In Slovenia, primary acellular pertussis vaccines (ACVs) containing pertactin (PRN) were mostly used during 1999-2016; ACVs without PRN were introduced in 2017. Among 123 Bordetella pertussis strains collected during 2002-2020, a total of 48 were PRN-deficient; 44 were collected after 2017. Changes to ACVs could increase PRN-deficient B. pertussis and infections.
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Funding information in the publication:
This study is partly supported by Tampere Tuberculosis Foundation (grant no. 26006205), Sigrid Juselius Foundation (grant no. 240045), and EUpertstrain project (project nos. 26004877 and 26004878).
