A2 Refereed review article in a scientific journal
Connecting the dots : Computational network analysis for disease insight and drug repurposing
Authors: Siminea, Nicoleta; Czeizler, Eugen; Popescu, Victor-Bogdan; Petre, Ion; Păun, Andrei
Publisher: Elsevier
Publication year: 2024
Journal: Current Opinion in Structural Biology
Journal name in source: Current Opinion in Structural Biology
Article number: 102881
Volume: 88
ISSN: 0959-440X
eISSN: 1879-033X
DOI: https://doi.org/10.1016/j.sbi.2024.102881
Web address : https://doi.org/10.1016/j.sbi.2024.102881
Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/457188188
Network biology is a powerful framework for studying the structure, function, and dynamics of biological systems, offering insights into the balance between health and disease states. The field is seeing rapid progress in all of its aspects: data availability, network synthesis, network analytics, and impactful applications in medicine and drug development. We review the most recent and significant results in network biomedicine, with a focus on the latest data, analytics, software resources, and applications in medicine. We also discuss what in our view are the likely directions of impactful development over the next few years.
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Funding information in the publication:
This work was partially supported by the Core Program within the Romanian National Research, Development and Innovation Plan 2022–2027, carried out with the support of MRID, project no. 23020101(SIA-PRO), contract no 7N/2022, and project PNRR-I8 no. 842027778., contract no 760096.
