A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Long-Term Impairment From Irritant-Induced Occupational Asthma
Tekijät: Lantto, Jussi; Suojalehto, Hille; Vasankari, Tuula; Karvala, Kirsi; Lindström, Irmeli
Kustantaja: Lippincott, Williams & Wilkins
Julkaisuvuosi: 2024
Journal: Journal of Occupational and Environmental Medicine
Tietokannassa oleva lehden nimi: Journal of occupational and environmental medicine
Lehden akronyymi: J Occup Environ Med
Vuosikerta: 66
Numero: 7
Aloitussivu: 597
Lopetussivu: 603
ISSN: 1076-2752
eISSN: 1536-5948
DOI: https://doi.org/10.1097/JOM.0000000000003120
Verkko-osoite: https://journals.lww.com/joem/fulltext/2024/07000/long_term_impairment_from_irritant_induced.11.aspx
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/457161305
Objective: The aim of the study is to assess the long-term physical condition, health-related quality of life, employment, and work ability of irritant-induced asthma (IIA) patients.
Methods: Forty-three IIA patients completed a follow-up questionnaire a median of eight (interquartile range 4-11) years after asthma diagnosis. We compared their results with those of 43 low-molecular-weight (LMW) sensitizer-induced occupational asthma (OA) patients and those of 206 adult-onset asthmatics in the general population.
Results: Of the IIA patients, 40% reported depressive symptoms. Of the <65-year-olds, 56% were employed, of whom 39% assessed their work ability as limited. IIA patients had more difficulty climbing several flights of stairs than LMW-induced OA patients (70% vs 47%, OR = 4.83 95% CI: 1.51-15.47). Most of the IIA patients' outcomes were inferior to those of the adult-onset asthmatics in the general population.
Conclusions: IIA prognosis appeared poor but resembled that of LMW-induced OA.
Ladattava julkaisu This is an electronic reprint of the original article. |
Julkaisussa olevat rahoitustiedot:
Funding sources: This project is funded by the Finnish Work Environment Fund, grant number 190390, and the Finnish Institute of Occupational Health. The corresponding author was supported by personal grants from the Research Foundation of Pulmonary Diseases and the Foundation of the Finnish Anti-Tuberculosis Association, and by a grant from the University of Helsinki donated by Finance Finland, Finnish Workers’ Compensation Center, and the Finnish Motor Insurers’ Centre. The sponsors played no role in the design of the study; in the collection, analysis or interpretation of the data; in the writing of the report; nor in the decision to submit this manuscript.