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Long-Term Impairment From Irritant-Induced Occupational Asthma




TekijätLantto, Jussi; Suojalehto, Hille; Vasankari, Tuula; Karvala, Kirsi; Lindström, Irmeli

KustantajaLippincott, Williams & Wilkins

Julkaisuvuosi2024

JournalJournal of Occupational and Environmental Medicine

Tietokannassa oleva lehden nimiJournal of occupational and environmental medicine

Lehden akronyymiJ Occup Environ Med

Vuosikerta66

Numero7

Aloitussivu597

Lopetussivu603

ISSN1076-2752

eISSN1536-5948

DOIhttps://doi.org/10.1097/JOM.0000000000003120

Verkko-osoitehttps://journals.lww.com/joem/fulltext/2024/07000/long_term_impairment_from_irritant_induced.11.aspx

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/457161305


Tiivistelmä

Objective: The aim of the study is to assess the long-term physical condition, health-related quality of life, employment, and work ability of irritant-induced asthma (IIA) patients.

Methods: Forty-three IIA patients completed a follow-up questionnaire a median of eight (interquartile range 4-11) years after asthma diagnosis. We compared their results with those of 43 low-molecular-weight (LMW) sensitizer-induced occupational asthma (OA) patients and those of 206 adult-onset asthmatics in the general population.

Results: Of the IIA patients, 40% reported depressive symptoms. Of the <65-year-olds, 56% were employed, of whom 39% assessed their work ability as limited. IIA patients had more difficulty climbing several flights of stairs than LMW-induced OA patients (70% vs 47%, OR = 4.83 95% CI: 1.51-15.47). Most of the IIA patients' outcomes were inferior to those of the adult-onset asthmatics in the general population.

Conclusions: IIA prognosis appeared poor but resembled that of LMW-induced OA.


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Julkaisussa olevat rahoitustiedot
Funding sources: This project is funded by the Finnish Work Environment Fund, grant number 190390, and the Finnish Institute of Occupational Health. The corresponding author was supported by personal grants from the Research Foundation of Pulmonary Diseases and the Foundation of the Finnish Anti-Tuberculosis Association, and by a grant from the University of Helsinki donated by Finance Finland, Finnish Workers’ Compensation Center, and the Finnish Motor Insurers’ Centre. The sponsors played no role in the design of the study; in the collection, analysis or interpretation of the data; in the writing of the report; nor in the decision to submit this manuscript.


Last updated on 2025-27-01 at 18:33