Low-Cost Tissue Oximetry Using Discrete Light-Emitting Diodes
: Panula, Tuukka; Mustajoki, Inka; Karhinoja Katri; Kjellman Maria; Sirkiä Jukka-Pekka; Kaisti, Matti
: IEEE Instrumentation and Measurement Technology Conference
: 2024
: IEEE International Instrumentation and Measurement Technology Conference
: 2024 IEEE International Instrumentation and Measurement Technology Conference (I2MTC) : Conference Proceedings
: 979-8-3503-8090-3
: 2642-2069
: 2642-2077
DOI: https://doi.org/10.1109/I2MTC60896.2024.10560647(external)
: https://research.utu.fi/converis/portal/detail/Publication/457104221(external)
Tissue oxygen saturation $(\text{StO}_{2})$ is an important biomarker used to monitor patients after a surgical intervention. $\text{StO}_{2}$ is often measured using various techniques that require expensive, bulky, and complicated instrumentation. We propose a low-cost instrument design to measure $\text{StO}_{2}$ level using discrete light-emitting diodes (LED) and a photodiode receiver. The instrument was tested using a liquid tissue phantom to verify the operation of the system in vitro during hemoglobin deoxygenation. A commercial spectrometer was used as a reference device. Furthermore, we tested the device in vivo by measuring skin $\text{StO}_{2}$ during a brachial artery occlusion test. The results of these experiments suggest that the device is capable of measuring $\text{StO}_{2}$ with sufficient accuracy and could provide a low-cost alternative to spectrometer-based tissue oximetry in clinical use.
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This project has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No 101115492. The work of Tuukka Panula was also supported by the Instrumentarium Science Foundation.