A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Sex differences in obstructive sleep apnoea
Tekijät: Maria R. Bonsignore, Tarja Saaresranta, Renata L. Riha
Kustantaja: European Respiratory Society
Julkaisuvuosi: 2019
Journal: European Respiratory Review
Tietokannassa oleva lehden nimi: European respiratory review : an official journal of the European Respiratory Society
Lehden akronyymi: Eur Respir Rev
Vuosikerta: 28
Numero: 154
Sivujen määrä: 11
ISSN: 0905-9180
eISSN: 1600-0617
DOI: https://doi.org/10.1183/16000617.0030-2019
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/44460904
Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have long been considered predominantly male-related conditions. The clinical presentation of sleep disordered breathing in females differs from males and can vary with age and physiological status, e.g. menopause and pregnancy. Overall, females appear to be more symptomatic, with lower apnoea–hypopnoea index scores compared to males. Furthermore, they appear to have more prolonged partial upper airway obstruction, and may report insomnia as a symptom of OSAHS more frequently. As a consequence of these differences in clinical presentation, females with sleep disordered breathing are often underdiagnosed and undertreated compared to males. This review is aimed at discussing the epidemiology, clinical presentation, pathophysiology and hormonal and metabolic differences in females who present with OSA/OSAHS in comparison to males.
Ladattava julkaisu This is an electronic reprint of the original article. |