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Rhinovirus C Is Associated With Severe Wheezing and Febrile Respiratory Illness in Young Children




TekijätErkkola Riku, Turunen Riitta, Räisänen Kati, Waris Matti, Vuorinen Tytti, Laine Miia, Tähtinen Paula, Gern James E., Bochkov Yury A., Ruohola Aino, Jartti Tuomas

KustantajaWilliams & Wilkins

Julkaisuvuosi2020

JournalPediatric Infectious Disease Journal

Tietokannassa oleva lehden nimiThe Pediatric infectious disease journal

Lehden akronyymiPediatr Infect Dis J

Vuosikerta39

Numero4

Aloitussivu283

Lopetussivu286

ISSN0891-3668

eISSN1532-0987

DOIhttps://doi.org/10.1097/INF.0000000000002570

Rinnakkaistallenteen osoitehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749725/


Tiivistelmä
Background:
Rhinovirus is the most common virus causing respiratory tract illnesses in children. Rhinoviruses are classified into species A, B and C. We examined the associations between different rhinovirus species and respiratory illness severity.
Methods:
This is a retrospective observational cohort study on confirmed rhinovirus infections in 134 children 3–23 months of age, who were enrolled in 2 prospective studies on bronchiolitis and acute otitis media, respectively, conducted simultaneously in Turku University Hospital, Turku, Finland, between September 2007 and December 2008.
Results:
Rhinovirus C is the most prevalent species in our study, and it was associated with severe wheezing and febrile illness. We also noted that history of atopic eczema was associated with wheezing.
Conclusions:
Our understanding of rhinovirus C as the most pathogenic rhinovirus species was fortified. Existing research supports the idea that atopic characteristics are associated with the severity of the rhinovirus C-induced illness.



Last updated on 2024-26-11 at 20:26