A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Occurrence and mortality of vasospastic angina pectoris hospitalised patients in Finland: a population-based registry cohort study




TekijätEssi Pikkarainen, Juuso Blomster, Jussi Sipilä, Päivi Rautava, Ville Kytö

Julkaisuvuosi2019

JournalBMJ Open

Artikkelin numeroe030768

Vuosikerta9

Numero11

Sivujen määrä7

ISSN2044-6055

DOIhttps://doi.org/10.1136/bmjopen-2019-030768

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/43999321


Tiivistelmä
OBJECTIVES:

The occurrence and mortality of vasospastic
angina pectoris (VAP) is largely unknown in western countries. Our
objective was to clarify the occurrence, gender-distribution and
mortality of VAP in Finland using a population-based hospital registry.

METHODS:

We
studied consecutive patients aged ≥18 years hospitalized with VAP as
the primary cause of admission in Finland during 2004-2014. The data
were collected from obligatory nationwide registries. During the study
period 1762 admissions were recorded.

RESULTS:

Majority
of all VAP patients were male (59.7%) and mean age was 65.7±12.0 years.
Annual admission rate for VAP was 2.29/100 000 person-years. Men were in
higher risk for VAP than women (admission rate 3.00/100 000 vs
1.68/100 000; RR 1.70; p<0.0001). Gender difference was not modified
by age. Likelihood of VAP was highest in population aged 70-84 years.
Admission rate for VAP decreased notably during the study period.
One-year all-cause mortality was 8.0% and 3-year mortality was 15.5%
(cardiac mortality 11.1%). Mortality was associated with increasing age,
comorbidity burden and lack of detected coronary artery obstruction,
but was similar between genders and during the study period.

CONCLUSIONS:

Men
have higher risk for vasospastic angina caused admissions. Likelihood
of vasospastic angina admission was highest in aged population. The
3-year all-cause mortality was 15.5%. Mortality was associated with
increasing age, comorbidities and non-obstructive VAP diagnosis but was
similar between genders.


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Last updated on 2024-26-11 at 22:56