A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Diffusion tensor imaging is associated with motor outcomes of very preterm born children at 11 years of age
Tekijät: Katri Lahti, Virva Saunavaara, Petriina Munck, Karoliina Uusitalo, Mari Koivisto, Riitta Parkkola, Leena Haataja, Annarilla Ahtola, Mikael Ekblad, Satu Ekblad, Eeva Ekholm, Leena Haataja, Mira Huhtala, Jere Jaakkola, Max Karukivi, Pentti Kero, Riikka Korja, Katri Lahti, Helena Lapinleimu, Liisa Lehtonen, Tuomo Lehtonen, Marika Leppänen, Annika Lind, Hanna Manninen, Mari Koivisto, Mira Mattson,Jonna Maunu, Petriina Munck, Laura Määttänen, Pekka Niemi, Anna Nyman, Pertti Palo, Riitta Parkkola, Liisi Ripatti, Päivi Rautava, Katriina Saarinen, Virva Saunavaara, Sirkku Setänen, Matti Sillanpää, Suvi Stolt, Päivi Tuomikoski‐Koiranen, Timo Tuovinen, Karoliina Uusitalo, Anniina Väliaho, Milla Ylijoki
Kustantaja: WILEY
Julkaisuvuosi: 2020
Journal: Acta Paediatrica
Tietokannassa oleva lehden nimi: ACTA PAEDIATRICA
Lehden akronyymi: ACTA PAEDIATR
Vuosikerta: 109
Numero: 4
Aloitussivu: 738
Lopetussivu: 745
Sivujen määrä: 8
ISSN: 0803-5253
eISSN: 1651-2227
DOI: https://doi.org/10.1111/apa.15004
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/43962304
Aim Very preterm children born <32 weeks of gestation are at risk for motor difficulties such as cerebral palsy and developmental coordination disorder. This study explores the association between diffusion tensor imaging metrics at term and motor outcomes at 11 years of age. Methods A cohort of 37 very preterm infants (mean gestational age 29 4/7, SD 2 0/7) born in 2004-2006 in Turku University Hospital underwent diffusion tensor imaging at term. A region of interest analysis of fractional anisotropy and mean diffusivity was performed. Motor outcomes at 11 years of age were measured with the Movement Assessment Battery for Children - Second Edition. Results The diffusion metrics of the corpus callosum (genu P = .005, splenium P = .049), the left corona radiata (P = .035) and the right optic radiation (P = .017) were related to later motor performance. Mean diffusivity decreased and fractional anisotropy increased in proportion to the improving performance. Conclusion The diffusion metrics of the genu and splenium of the corpus callosum, the left corona radiata and the right optic radiation at term were associated with motor skills at 11 years of age. Diffusion tensor imaging should be further studied as a potential tool in recognising children at risk for motor impairment.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
