A1 Refereed original research article in a scientific journal

ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection




AuthorsShahab Nozohoor, Khalil Ahmad, Markus Bjurbom, Emma C. Hansson, Alexandra Heimisdottir, Anders Jeppsson, Ari Mennander, Christian Olsson, Emily Pan, Sigurdur Ragnarsson, Johan Sjögren, George Tellides, Anders Wickbom, Arnar Geirsson, Tomas Gudbjartsson, Igor Zindovic

PublisherTAYLOR & FRANCIS LTD

Publication year2019

JournalScandinavian Cardiovascular Journal

Journal name in sourceSCANDINAVIAN CARDIOVASCULAR JOURNAL

Journal acronymSCAND CARDIOVASC J

Volume54

Issue2

First page 124

Last page129

Number of pages6

ISSN1401-7431

eISSN1651-2006

DOIhttps://doi.org/10.1080/14017431.2019.1679387

Self-archived copy’s web addresshttps://research.utu.fi/converis/portal/detail/Publication/43812494


Abstract
Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7-43.4)% vs 39.0 (95% CI 39.0-39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.

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