Educational Recommendations on Selected Analytical and Clinical Aspects of Natriuretic Peptides with a Focus on Heart Failure: A Report from the IFCC Committee on Clinical Applications of Cardiac Bio-Markers

: Kaysak PA, Lam CSP, Saenger AK, Jaffe AS, Collinson P, Pulkki K, Omland T, Lefeyre G, Body R, Ordonez-Llanos J, Apple FS

Publisher: AMER ASSOC CLINICAL CHEMISTRY

: Minneapolis

: 2019

: Clinical Chemistry

: CLINICAL CHEMISTRY

: CLIN CHEM

: 65

: 10

: 1221

: 1227

: 7

: 0009-9147

: 1530-8561

DOI: https://doi.org/10.1373/clinchem.2019.306621

: 10.1373/clinchem.2019.306621

The IFCC Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has directives and initiatives focused on providing evidence-based educational resources to aid and improve understanding around key analytical and clinical aspects of cardiac biomarkers used in clinical practice and the research setting. As a task force, we have previously published position statements and recommendations focused on use and analytical aspects of high-sensitivity cardiac troponin assays. The current educational document is the first from the C-CB highlighting important biochemical, analytical, and clinical aspects as they relate to the natriuretic peptides (NPs), including B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NTproBNP), with a focus on heart failure. (C) 2019 American Association for Clinical Chemistry