A1 Refereed original research article in a scientific journal

Youth and Long-Term Dietary Calcium Intake With Risk of Impaired Glucose Metabolism and Type 2 Diabetes in Adulthood



Authors: Feitong Wu, Markus Juonala, Katja Pahkala, Marie-Jeanne Buscot, Matthew A Sabin, Niina Pitkänen, Tapani Rönnemaa, Antti Jula, Terho Lehtimäki, Nina Hutri-Kähönen, Mika Kähönen, Tomi Laitinen,Jorma S A Viikari, Olli T Raitakari, Costan G Magnussen

Publisher: Oxford Academic

Publication year: 2019

Journal: Journal of Clinical Endocrinology and Metabolism

Journal name in source: The Journal of clinical endocrinology and metabolism

Journal acronym: JCEM

Volume: 104

Issue: 6

First page : 2067

Last page: 2074

Number of pages: 8

ISSN: 1945-7197

eISSN: 1945-7197

DOI: https://doi.org/10.1210/jc.2018-02321

Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/40459439


Abstract
CONTEXT:

To the best of our knowledge, no previous studies have examined the role of youth calcium intake in the development of impaired glucose metabolism, especially those with long-term high calcium intake.

OBJECTIVES:

To examine whether youth and long-term (between youth and adulthood) dietary calcium intake is associated with adult impaired glucose metabolism and type 2 diabetes (T2D).

DESIGN, SETTING, AND PARTICIPANTS:

The Cardiovascular Risk in Young Finns Study is a 31-year prospective cohort study (n = 1134; age, 3 to 18 years at baseline).

EXPOSURES:

Dietary calcium intake was assessed at baseline (1980) and adult follow-up visits (2001, 2007, and 2011). Long-term (mean between youth and adulthood) dietary calcium intake was calculated.

MAIN OUTCOME MEASURES:

Adult impaired fasting glucose (IFG) and T2D.

RESULTS:

We found no evidence for nonlinear associations between calcium intake and IFG or T2D among females and males (all P for nonlinearity > 0.05). Higher youth and long-term dietary calcium intake was not associated with the risk of IFG or T2D among females or males after adjustment for confounders, including youth and adult body mass index.

CONCLUSIONS:

Youth or long-term dietary calcium intake is not associated with adult risk of developing impaired glucose metabolism or T2D.


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Last updated on 2024-26-11 at 22:04