A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits
Tekijät: Dashti HS, Follis JL, Smith CE, Tanaka T, Garaulet M, Gottlieb DJ, Hruby A, Jacques PF, Kiefte-de Jong JC, Lamon-Fava S, Scheer FAJL, Bartz TM, Kovanen L, Wojczynski MK, Frazier-Wood AC, Ahluwalia TS, Perala MM, Jonsson A, Muka T, Kalafati IP, Mikkila V, Ordovas JM; for the CHARGE Nutrition Study Group
Kustantaja: AMER DIABETES ASSOC
Julkaisuvuosi: 2015
Journal: Diabetes Care
Tietokannassa oleva lehden nimi: DIABETES CARE
Lehden akronyymi: DIABETES CARE
Vuosikerta: 38
Numero: 8
Aloitussivu: 1456
Lopetussivu: 1466
Sivujen määrä: 11
ISSN: 0149-5992
eISSN: 1935-5548
DOI: https://doi.org/10.2337/dc14-2709
Our results suggest that lower carbohydrate intake and normal sleep duration may ameliorate cardiometabolic abnormalities conferred by common circadian-related genetic variants. Until further mechanistic examination of the nominally significant interactions is conducted, recommendations applicable to the general population regarding diet-specifically higher carbohydrate and lower fat composition-and normal sleep duration should continue to be emphasized among individuals with the investigated circadian-related gene variants.
