Long-Term Real-Life Experience With Rituximab in Adult Finnish Patients With Rheumatoid Arthritis Refractory or With Contraindication to Anti-Tumor Necrosis Factor Drugs
: Valleala H, Korpela M, Hienonen-Kempas T, Immonen K, Lahteenmaki J, Uusitalo T, Komulainen R, Mottonen T, Hannonen P
Publisher: LIPPINCOTT WILLIAMS & WILKINS
: 2015
: JCR: Journal of Clinical Rheumatology
: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY
: JCR-J CLIN RHEUMATOL
: 21
: 1
: 24
: 30
: 7
: 1076-1608
DOI: https://doi.org/10.1097/RHU.0000000000000166
Conclusions: The treatment as-needed regimen used in this study cohort led to delayed RTX retreatment and disease flare in a significant proportion of patients. A regular retreatment every 6 months, at least, after the first 2 treatment courses in patients who are not in remission could allow better control of disease activity.