Long-Term Real-Life Experience With Rituximab in Adult Finnish Patients With Rheumatoid Arthritis Refractory or With Contraindication to Anti-Tumor Necrosis Factor Drugs - UTU Research Portal

A1 Refereed original research article in a scientific journal

Long-Term Real-Life Experience With Rituximab in Adult Finnish Patients With Rheumatoid Arthritis Refractory or With Contraindication to Anti-Tumor Necrosis Factor Drugs

Authors: Valleala H, Korpela M, Hienonen-Kempas T, Immonen K, Lahteenmaki J, Uusitalo T, Komulainen R, Mottonen T, Hannonen P

Publisher: LIPPINCOTT WILLIAMS & WILKINS

Publication year: 2015

Journal: JCR: Journal of Clinical Rheumatology

Journal name in source: JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Journal acronym: JCR-J CLIN RHEUMATOL

Volume: 21

Issue: 1

First page : 24

Last page: 30

Number of pages: 7

ISSN: 1076-1608

DOI: https://doi.org/10.1097/RHU.0000000000000166

Abstract

Conclusions: The treatment as-needed regimen used in this study cohort led to delayed RTX retreatment and disease flare in a significant proportion of patients. A regular retreatment every 6 months, at least, after the first 2 treatment courses in patients who are not in remission could allow better control of disease activity.