A1 Refereed original research article in a scientific journal

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Authors: Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu YC, Turcot V, Auer PL, Fine RS, Guo XQ, Schurmann C, Lempradl A, Marouli E, Mahajan A, Winkler TW, Locke AE, Medina-Gomez C, Esko T, Vedantam S, Giri A, Lo KS, Alfred T, Mudgal P, Ng MCY, Heard-Costa NL, Feitosa MF, Manning AK, Willems SM, Sivapalaratnam S, Abecasis G, Alam DS, Allison M, Amouyel P, Arzumanyanm Z, Balkau B, Bastarache L, Bergmann S, Bielak LF, Blueher M, Boehnke M, Boeing H, Boerwinkle E, Boger CA, Bork-Jensen J, Bottinger EP, Bowden DW, Brandslund I, Broer L, Burt AA, Butterworth AS, Caulfield M, Cesana G, Chambers JC, Chasman DI, Chen YDI, Chowdhury R, Christensen C, Chu A, Collins FS, Cook JP, Cox AJ, Crosslin DS, Danesh J, de Bakker PIW, de Denus S, de Mutsert R, Dedoussis G, Demerath EW, Dennis JG, Denny JC, Di Angelantonio E, Dorr M, Drenos F, Dube MP, Dunning AM, Easton DF, Elliott P, Evangelou E, Farmaki AE, Feng S, Ferrannini E, Ferrieres J, Florez JC, Fornage M, Fox CS, Franks PW, Friedrich N, Gan W, Gandin I, Gasparini P, Giedraitis V, Girotto G, Gorski M, Grallert H, Grarup N, Groves ML, Gustafsson S, Haessler J, Hansen T, Hattersley AT, Hayward C, Heid IM, Holmen OL, Hovingh GK, Howson JMM, Hu Y, Hung YJ, Hveem K, Ikram MA, Ingelsson E, Jackson AU, Jarvik GP, Jia YC, Jorgensen T, Jousilahti P, Justesen JM, Kahali B, Karaleftheri M, Kardia SLR, Karpe F, Kee F, Kitajima H, Komulainen P, Kooner JS, Kovacs P, Kramer BK, Kuulasmaa K, Kuusisto J, Laakso M, Lakka TA, Lamparter D, La Nge LA, Langenberg C, Larson EB, Lee NR, Lee WJ, Lehtimaki T, Lewis CE, Li HX, Li J, RuifangLi-Gao, Lin LA, Lin X, Lind L, Lindstrom J, Linneberg A, Liu CT, Liu DJJ, Luan J, Lyytikainen LP, MacGregor S, Magi R, Mannisto S, Marenne G, Marten J, Mascal NGD, McCarthy MI, Meidtner K, Mihailov E, Moilanen L, Moitry M, Mook-Kanamori DO, Morgan A, Morris AP, Muller-Nurasyid M, Munroe PB, Narisu N, Nelson CP, Neville M, Ntalla I, Owen KR, Pedersen O, Peloso GM, Pennell CE, Perola M, James A, Perry JRB, Pers TH, Ewing A, Polasek O, Rasheed A, Raulerson CK, Rauramaa R, Reilly DF, Reiner AP, Ridker PM, Rivas MA, Robertson NR, Robino A, Rudan I, Ruth KS, Saleheen D, Salomaa V, Samani NJ, Schreiner PJ, Schulze MB, Scott RA, Segura-Lepe M, Sim XL, Slater AJ, Small KS, Smith BH, Smith JA, Southam L, Spector TD, Speliotes EK, Stefansson K, Steinthorsdottir V, Stirrups KE, Strauch K, Stringham HM, Stumvoll M, Sun L, Surendran P, Swart KMA, Tardif JC, Taylor KD, Teumer A, Thompson DJ, Thorleifsson G, Thorsteinsdottir U, Thuesen BH, Tonjes A, Torres M, Tsafantakis E, Tuomilehto J, Uitterlinden AG, Uusitupa M, van Duijn CM, Vanhala M, Varma R, Vermeulen SH, Vestergaard H, Vitart V, Vogt TF, Vuckovic D, Wagenknecht LE, Walker M, Wallentin L, Wang FJ, Wang CA, Wang S, Wareham NIJ, Warren HR, Waterworth DM, Wessel J, White HD, Willer CJ, Wilson JG, Wood AR, Wu Y, Yaghootkar H, Yao J, Verges-Armstrong LM, Young R, Zeggini E, Zhan XW, Zhang WH, Zhao JH, Zhao W, Zheng H, Zhou W, Zillikens MC, Rivadeneira F, Borecki IB, Pospisilik JA, Deloukas P, Frayling TM, Lettre G, Mohlke KL, Rotter JI, Kutalik Z, Hirschhorn JN, Cupples LA, Loos RJF, North KE, Lindgren CM, O'Connell JR, Raitakari OT, Danesh J, Surendran P, Young R, Liu CT, Borecki IB, Cupples LA, North KE, Boerwinkle E, Fornage M, Wilson JG, Lange LA, Ikram MA, Uitterlinden AG, Justice AE, Highland HM, Young KL, Graff M, Grove ML, Heard-Costa NL, Zillikens MC, Danesh J, Surendran P, Young R, Cook JP, Warren HR, Yaghootkar H, Masca NGD, Mihailov E, Marten J, Stirrups KE, Neville M, Robertson NR, Zhang WH, Evangelou E, Nelson CP, Luan JA, Scott RA, Farmaki AE, Polasek O, Rudan I, Franks PW, Spector TD, Wareham NJ, Esko T, Ingelsson E, De Bakker PI, Chambers JC, Kooner JS, Karpe F, Tuomilehto J, Morris AP, Hveem K, Willer CJ, Salomaa V, McCarthy MI, Elliott P, Zeggini E, Hayward C, Caulfield MJ, Mahajan A, Morris AP, Samani NJ, Lindgren CM, Munroe PB, Willer CJ, Manning AK, Sim XL, Locke AE, Jackson AU, Stringham HM, Boehnke M, Tuomilehto J, Collins FS, Mohlke KL, Abecasis G, Muller-Nurasyid M, Rivas MA, Mahajan A, Small KS, Lindgren CM, Robertson NR, Morris AP, Hattersley AT, Spector TD, Frayling TM, McCarthy MI, Willems SM, Manning AK, Frayling TM, Florez JC, Chambers JC, Kooner JS, Zhang WH, McCarthy MI, Lindgren CM, Mahajan A, Morris AP, Rivas MA, Willems SM, Laakso M, Boehnke M, Sim XL, Locke AE, Abecasis G, Wilson JG, Highland HM, Bowden DW, Zeggini E, Boehnke M, Florez JC, McCarthy MI, McCarthy MI, Florez JC

Publisher: NATURE PUBLISHING GROUP

Publication year: 2019

Journal: Nature Genetics

Journal name in source: NATURE GENETICS

Journal acronym: NAT GENET

Volume: 51

Issue: 3

First page : 452

Last page: 469

Number of pages: 21

ISSN: 1061-4036

DOI: https://doi.org/10.1038/s41588-018-0334-2

Self-archived copy’s web address: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560635/